(data stored in ACNUC7421 zone)

HOGENOM: ALKOO_1_PE1011

ID   ALKOO_1_PE1011                       STANDARD;      PRT;   739 AA.
AC   ALKOO_1_PE1011; A8MG43;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase; EC=5.99.1 2; (ALKOO_1.PE1011).
GN   OrderedLocusNames=Clos_1034;
OS   ALKALIPHILUS OREMLANDII OHILAS.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Alkaliphilus.
OX   NCBI_TaxID=350688;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ALKOO_1.PE1011.
CC       Alkaliphilus oremlandii OhILAs, complete genome.
CC       pAACI03, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:A8MG43_ALKOO
CC   -!- CATALYTIC ACTIVITY: ATP-independent breakage of single-stranded
CC       DNA, followed by passage and rejoining.
CC   -!- SIMILARITY: Belongs to the prokaryotic type I/III topoisomerase
CC       family.
CC   -!- SIMILARITY: Contains 1 Toprim domain.
CC   -!- GENE_FAMILY: HOG000086847 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A8MG43; -.
DR   EMBL; CP000853; ABW18581.1; -; Genomic_DNA.
DR   RefSeq; YP_001512577.1; NC_009922.1.
DR   ProteinModelPortal; A8MG43; -.
DR   STRING; A8MG43; -.
DR   GeneID; 5677984; -.
DR   GenomeReviews; CP000853_GR; Clos_1034.
DR   KEGG; aoe:Clos_1034; -.
DR   OMA; AFEYEQT; -.
DR   ProtClustDB; PRK07726; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR000380; Topo_IA.
DR   InterPro; IPR003601; Topo_IA_2.
DR   InterPro; IPR023406; Topo_IA_AS.
DR   InterPro; IPR013497; Topo_IA_cen.
DR   InterPro; IPR013824; Topo_IA_cen_sub1.
DR   InterPro; IPR013825; Topo_IA_cen_sub2.
DR   InterPro; IPR023405; Topo_IA_core_domain.
DR   InterPro; IPR003602; Topo_IA_DNA-bd.
DR   InterPro; IPR005738; TopoIII_bac.
DR   InterPro; IPR006171; Toprim_domain.
DR   Gene3D; G3DSA:1.10.460.10; Topo_IA_cen_sub1; 2.
DR   Gene3D; G3DSA:2.70.20.10; Topo_IA_cen_sub2; 2.
DR   PANTHER; PTHR11390; Topo_IA; 1.
DR   Pfam; PF01131; Topoisom_bac; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   PRINTS; PR00417; PRTPISMRASEI.
DR   SMART; SM00437; TOP1Ac; 1.
DR   SMART; SM00436; TOP1Bc; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   SUPFAM; SSF56712; Topo_IA_core; 1.
DR   TIGRFAMs; TIGR01056; TopB; 1.
DR   PROSITE; PS00396; TOPOISOMERASE_I_PROK; 1.
DR   HOGENOMDNA; ALKOO_1.PE1011; -.
KW   DNA topoisomerase III;
KW   ATP-binding; Complete proteome; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   739 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MYHHRIERIV NMNKKLVLAE KPSVGRDLAR VLNCNKKGNG YLEGQEYIVT WALGHLVTLA
     DPENYSDRYK SWKIEDLPIL PSDLKLVVIK KTGKQFQTIK EQMHRKDVNE IIIATDAGRE
     GELVARWIIE KAKVQKPIQR LWISSVTDNA IKDGFKKLKN GKDYEKLYQS AVARAEVDWI
     VGINATRALT CKYNAQLSCG RVQTPTLAII AQREAEIQNF KSRTFYGMEA MSPHLKLTWQ
     DRKTKDIRSF EKEKITSILN AIKNKDGYVM DVEKKYKKSY APKLYDLTEL QRDANRIFGY
     SAKETLGIMQ QLYENYKILT YPRTDSRYIT SDIVPTLKDR IKACGVGPYK LAANKVLQGS
     IKGNSSFVDD GKVSDHHAII PTEQFVQLSS LSDKERKVYD LVVKRFLAVL YPPFEYEETF
     IRAKIGEEVF IAKGKNVIHQ GWKEVYGNMD EDESGNEDIS EQLLPRVNKG DVLKISSITQ
     TTGQTKPPAP FNEGTLLSAM ENPVKYMKDA HKDLIKTIGE TGGLGTVATR ADIIEKLFST
     FLIEKRGNDI WITSKGKQLL ELVPEDLKSP ALTADWEQKL GAISKGDLHR DHFVKEMKAY
     TKTVVDEIKN SDETFKHDNL TRNKCPECGK YMLEVKGKRG KMLVCQSREC GYRKGVTQNT
     NARCPNCHKK LELRGEGEGQ IFVCSCGHRE KLATFKERKK QEGSKVSKKE VVKYMNQQKK
     ENDGFANTAL ADALSKLKF
//

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