(data stored in SCRATCH3701 zone)

HOGENOM6: AMICL_1_PE248

ID   AMICL_1_PE248                        STANDARD;      PRT;   817 AA.
AC   AMICL_1_PE248; D5ECW5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (AMICL_1.PE248).
GN   Name=gyrA; OrderedLocusNames=Amico_0252;
OS   AMINOBACTERIUM COLOMBIENSE DSM 12261.
OC   Bacteria; Synergistetes; Synergistia; Synergistales; Synergistaceae;
OC   Aminobacterium.
OX   NCBI_TaxID=572547;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AMICL_1.PE248.
CC       Aminobacterium colombiense DSM 12261 chromosome, complete genome.
CC       Missing 5 prime End;
CC   -!- ANNOTATIONS ORIGIN:GYRA_AMICL
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D5ECW5; -.
DR   EMBL; CP001997; ADE56397.1; -; Genomic_DNA.
DR   RefSeq; YP_003553121.1; NC_014011.1.
DR   GeneID; 8963150; -.
DR   GenomeReviews; CP001997_GR; Amico_0252.
DR   KEGG; aco:Amico_0252; -.
DR   OMA; QRENVIV; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; AMICL_1.PE248; -.
DR   PRODOM; AMICL_1_PE248.
DR   SWISS-2DPAGE; AMICL_1_PE248.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   817 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEEKKGEPLF GKVVPLPLVE EIKHSYLDYA MSVIVGRALP DARDGLKPVQ RRILYAMMEL
     GLRHNTAYKK SARVVGETMG KYHPHGDSAI YDTMVRMAQD FSMRYPLVDG QGNFGSIDGD
     PAAAMRYTEA RLYEIGELML ADIDQDTVDW GPNFDESLQE PLCLPAMLPN LLINGSSGIA
     VGMATNIPPH NLVEVVDALC YLIDTEPEQV DIGEILFRMP GPDFPTGGLI LGRDGIIDAY
     RTGRGKITMR GRTHIEEGKR GKTFIVITEI PYMVNKTNLI ETIAKNVQDK TIDGVMDLRD
     ESDREGLRIV IEVNRDTDPN LVLRQLYRRT QLQSTFGVIN LALIDGYPKE LSIEEMLNIF
     LNHRRSVVRR RTQFRLEKAE ARAHIVEGLV KALDIIDEVI ALIRGSATTE EAKEGLISKL
     DFSEAQAQAI LEMRLQRLTG LEREKLEAEL AQLLSDIERY QTILGNPKVL DSVIKEELLE
     VKRRFGNERK TEIIDAVEDV SIEDLIPESD IVVVLSRDGY LRRKDLQEYT LQGRGGKGRK
     GTALQEEDEV ALVAVTSTHR DIYLFTSKGR VLALKGYVIP ESKTGRGKLI NRFVALEEGE
     RVVTMHGRAV DGAKYAFFIT LRGTAKRLDL SELENLTRAG RRVMGLDEGD EISQIVLTSG
     DDHLLIVTAQ GQALRTHESE FRPMGRTARG VRGIRLRKND YVIGCDVVAN GRWPLLLSEN
     GFGKRTKYDE FSLRHRGGSG VIVMNLSDRT GLIVGCWSVA EGDEIVAITS RGRMIRLAVS
     ESPVLGRTAM GSIMMRLDEG DTVATASVVS TEDGEDD
//

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