(data stored in ACNUC30567 zone)

HOGENOM: ANOGA_100_PE97

ID   ANOGA_100_PE97                       STANDARD;      PRT;   218 AA.
AC   ANOGA_100_PE97; P46428; Q7PGA2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   Flags: Fragments;
DE   RecName: Full=Glutathione S-transferase; EC=2.5.1 18;AltName: Full=GST
DE   class-sigma; (ANOGA_100.PE97).
GN   Name=GstS1; ORFNames=AGAP010404;
OS   ANOPHELES GAMBIAE.
OC   Anophelinae; Pyretophorus; Pterygota; Protostomia; Pancrustacea;
OC   Panarthropoda; Neoptera; Nematocera; Metazoa; Mandibulata; Insecta;
OC   Hexapoda; Eumetazoa; Eukaryota; Endopterygota; Diptera; Dicondylia;
OC   Culicoidea; Culicimorpha; Culicidae; Coelomata; Bilateria; Arthropoda;
OC   Anopheles.
OX   NCBI_TaxID=7165;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ANOGA_100.PE97.
CC       Anopheles gambiae chromosome 3L_hap_26 AgamP3  sequence 1..41961389
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:GST_ANOGA
CC   -!- FUNCTION: Conjugation of reduced glutathione to a wide number of
CC       exogenous and endogenous hydrophobic electrophiles.
CC   -!- CATALYTIC ACTIVITY: RX + glutathione = HX + R-S-glutathione.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=A;
CC         IsoId=P46428-1; Sequence=Displayed;
CC         Note=No experimental confirmation available;
CC       Name=B;
CC         IsoId=P46428-2; Sequence=VSP_029900;
CC   -!- SIMILARITY: Belongs to the GST superfamily. Sigma family.
CC   -!- SIMILARITY: Contains 1 GST C-terminal domain.
CC   -!- SIMILARITY: Contains 1 GST N-terminal domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA29358.1; Type=Erroneous initiation;
CC       Sequence=EAA45010.4; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000115733 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Anopheles_gambiae;AGAP010404;AGAP010404-RA;AGAP010404-PA.
DR   EMBL; AAAB01008849; - ;
DR   EMBL; L07880; - ;
DR   UniProtKB/Swiss-Prot; P46428; Q7PGA2; -.
DR   EMBL; L07880; AAA29358.1; ALT_INIT; mRNA.
DR   EMBL; AAAB01008849; EAA45010.4; ALT_INIT; Genomic_DNA.
DR   RefSeq; XP_311546.4; XM_311546.4.
DR   ProteinModelPortal; P46428; -.
DR   SMR; P46428; 4-203.
DR   EnsemblMetazoa; AGAP010404-RA; AGAP010404-PA; AGAP010404.
DR   GeneID; 1272645; -.
DR   KEGG; aga:AgaP_AGAP010404; -.
DR   VectorBase; AGAP010404; Anopheles gambiae.
DR   eggNOG; inNOG04427; -.
DR   InParanoid; P46428; -.
DR   OrthoDB; EOG4N02WZ; -.
DR   GO; GO:0004364; F:glutathione transferase activity; IEA:EC.
DR   InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
DR   InterPro; IPR004046; GST_C.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   Gene3D; G3DSA:1.20.1050.10; GST_C_like; 1.
DR   Gene3D; G3DSA:3.40.30.10; Thioredoxin_fold; 1.
DR   Pfam; PF00043; GST_C; 1.
DR   Pfam; PF02798; GST_N; 1.
DR   SUPFAM; SSF47616; GST_C_like; 1.
DR   SUPFAM; SSF52833; Thiordxn-like_fd; 1.
DR   PROSITE; PS50405; GST_CTER; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
DR   HOGENOMDNA; ANOGA_100.PE97; -.
KW   AGAP01040400017784; AGAP010404-PA17508; P46428; AAAB01008849; L07880;
KW   Alternative splicing; Complete proteome; Reference proteome;
KW   Transferase.
SQ   SEQUENCE   218 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     LSSSSISRSS LKCNIMPDYK VYYFNVKALG EPLRFLLSYG NLPFDDVRIT REEWPALKPT
     MPMGQMPVLE VDGKKVHQSV AMSRYLANQV GLAGADDWEN LMIDTVVDTV NDFRLKIAIV
     AYEPDDMVKE KKMVTLNNEV IPFYLTKLNV IAKENNGHLV LGKPTWADVY FAGILDYLNY
     LTKTNLLENF PNLQEVVQKV LDNENVKAYI AKRPITEV
//

If you have problems or comments...

PBIL Back to PBIL home page