HOGENOM: ANOGA_61_PE1607

ID   ANOGA_61_PE1607                      STANDARD;      PRT;   191 AA.
AC   ANOGA_61_PE1607; Q17031; Q7PQZ1; Q93110;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Cdc42 homolog;AltName: Full=25 kDa GTP-binding
DE   protein;Flags: Precursor; (ANOGA_61.PE1607).
GN   Name=Cdc42; ORFNames=AGAP002440;
OS   ANOPHELES GAMBIAE.
OC   Anophelinae; Pyretophorus; Pterygota; Protostomia; Pancrustacea;
OC   Panarthropoda; Neoptera; Nematocera; Metazoa; Mandibulata; Insecta;
OC   Hexapoda; Eumetazoa; Eukaryota; Endopterygota; Diptera; Dicondylia;
OC   Culicoidea; Culicimorpha; Culicidae; Coelomata; Bilateria; Arthropoda;
OC   Anopheles.
OX   NCBI_TaxID=7165;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ANOGA_61.PE1607.
CC       Anopheles gambiae chromosome 2R_hap_55 AgamP3  sequence 1..61548419
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:CDC42_ANOGA
CC   -!- FUNCTION: Regulates mbt kinase activity and is also required to
CC       recruit mbt to adheren junctions. Together with mbt, regulates
CC       photoreceptor cell morphogenesis (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell junction, adherens junction (By
CC       similarity). Cell membrane; Lipid-anchor (By similarity).
CC   -!- TISSUE SPECIFICITY: Highly expressed in the adult unfed gut,
CC       expression drops after feeding.
CC   -!- DEVELOPMENTAL STAGE: Expressed throughout development with highest
CC       levels in early embryo and pupae and lowest levels in late pupae
CC       and adults.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rho family.
CC       CDC42 subfamily.
CC   -!- GENE_FAMILY: HOG000233974 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Anopheles_gambiae;AGAP002440;AGAP002440-RA;AGAP002440-PA.
DR   EMBL; AAAB01008859; - ;
DR   EMBL; Z69980; - ;
DR   UniProtKB/Swiss-Prot; Q17031; Q7PQZ1; Q93110; -.
DR   EMBL; AAAB01008859; EAA08093.4; -; Genomic_DNA.
DR   EMBL; Z69980; CAA93820.1; -; mRNA.
DR   RefSeq; XP_312505.3; XM_312505.4.
DR   ProteinModelPortal; Q17031; -.
DR   SMR; Q17031; 1-191.
DR   STRING; Q17031; -.
DR   EnsemblMetazoa; AGAP002440-RA; AGAP002440-PA; AGAP002440.
DR   EnsemblMetazoa; AGAP002440-RB; AGAP002440-PB; AGAP002440.
DR   EnsemblMetazoa; AGAP002440-RC; AGAP002440-PC; AGAP002440.
DR   GeneID; 1273521; -.
DR   KEGG; aga:AgaP_AGAP002440; -.
DR   VectorBase; AGAP002440; Anopheles gambiae.
DR   eggNOG; inNOG07769; -.
DR   GeneTree; EMGT00050000000001; -.
DR   InParanoid; Q17031; -.
DR   OMA; EITHHCQ; -.
DR   OrthoDB; EOG4NCJVT; -.
DR   PhylomeDB; Q17031; -.
DR   GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR003578; Small_GTPase_Rho.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00174; RHO; 1.
DR   TIGRFAMs; TIGR00231; Small_GTP; 1.
DR   PROSITE; PS51420; RHO; 1.
DR   HOGENOMDNA; ANOGA_61.PE1607; -.
KW   AGAP00244000017784; AGAP002440-PA17508; Q17031; AAAB01008859; Z69980;
KW   Cell junction; Cell membrane; Complete proteome;
KW   Developmental protein; GTP-binding; Lipoprotein; Membrane;
KW   Methylation; Nucleotide-binding; Prenylation; Reference proteome.
SQ   SEQUENCE   191 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQTIKCVVVG DGAVGKTCLL ISYTTNKFPS EYVPTVFDNY AVTVMIGGEP YTLGLFDTAG
     QEDYDRLRPL SYPQTDVFLV CFSVVSPSSF ENVKEKWVPE ITHHCQKTPF LLVGTQIDLR
     DENSTLEKLA KNKQKPITLE QGEKLAKELK AVKYVECSAL TQKGLKNVFD EAILAALEPP
     EPTKKRKCRF L
//