(data stored in ACNUC7421 zone)

HOGENOM: ARATH_2_PE1445

ID   ARATH_2_PE1445                       STANDARD;      PRT;   949 AA.
AC   ARATH_2_PE1445; P20649; O64626;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=ATPase 1, plasma membrane-type; EC=3.6.3 6;AltName:
DE   Full=Proton pump 1; (ARATH_2.PE1445).
GN   Name=AHA1; OrderedLocusNames=At2g18960; ORFNames=F19F24.16;
OS   ARABIDOPSIS THALIANA.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicots; rosids;
OC   eurosids II; Brassicales; Brassicaceae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ARATH_2.PE1445.
CC       Arabidopsis thaliana chromosome 2 TAIR10 full sequence 1..19698289
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:PMA1_ARATH
CC   -!- FUNCTION: The plasma membrane H(+) ATPase of plants and fungi
CC       generates a proton gradient that drives the active transport of
CC       nutrients by H(+)-symport. The resulting external acidification
CC       and/or internal alkinization may mediate growth responses.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O + H(+)(In) = ADP + phosphate +
CC       H(+)(Out).
CC   -!- SUBUNIT: Binds to 14-3-3 proteins. The binding is induced by
CC       phosphorylation of Thr-948. Binding to 14-3-3 proteins activates
CC       the H(+)-ATPase (By similarity).
CC   -!- INTERACTION:
CC       O23144:ppi; NbExp=7; IntAct=EBI-2354448, EBI-2354477;
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (Probable).
CC   -!- PTM: Phosphorylation level varies significantly during early
CC       response to general elicitors.
CC   -!- SIMILARITY: Belongs to the cation transport ATPase (P-type)
CC       (TC 3.A.3) family. Type IIIA subfamily.
CC   -!- GENE_FAMILY: HOG000160005 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Arabidopsis_thaliana;AT2G18960;AT2G18960.1;AT2G18960.1.
DR   EMBL; AC003673; - ;
DR   EMBL; AK220788; - ;
DR   EMBL; AK221932; - ;
DR   EMBL; BT008692; - ;
DR   EMBL; M24107; - ;
DR   UniProtKB/Swiss-Prot; P20649; O64626; -.
DR   EMBL; M24107; AAA32813.1; -; mRNA.
DR   EMBL; AC003673; AAC09030.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06832.1; -; Genomic_DNA.
DR   EMBL; BT008692; AAP40498.1; -; mRNA.
DR   IPI; IPI00526113; -.
DR   PIR; T01624; PXMUP1.
DR   RefSeq; NP_179486.1; NM_127453.3.
DR   UniGene; At.24695; -.
DR   ProteinModelPortal; P20649; -.
DR   SMR; P20649; 12-844, 900-949.
DR   IntAct; P20649; 4.
DR   MINT; MINT-6822995; -.
DR   STRING; P20649; -.
DR   TCDB; 3.A.3.3.7; P-type ATPase (P-ATPase) superfamily.
DR   PRIDE; P20649; -.
DR   ProMEX; P20649; -.
DR   EnsemblPlants; AT2G18960.1; AT2G18960.1; AT2G18960.
DR   GeneID; 816413; -.
DR   GenomeReviews; CT485783_GR; AT2G18960.
DR   KEGG; ath:AT2G18960; -.
DR   NMPDR; fig|3702.1.peg.8893; -.
DR   TAIR; At2g18960; -.
DR   eggNOG; KOG0205; -.
DR   InParanoid; P20649; -.
DR   OMA; DNNDELM; -.
DR   PhylomeDB; P20649; -.
DR   ProtClustDB; CLSN2683068; -.
DR   ArrayExpress; P20649; -.
DR   Genevestigator; P20649; -.
DR   GermOnline; AT2G18960; Arabidopsis thaliana.
DR   GO; GO:0016021; C:integral to membrane; IDA:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR   GO; GO:0005773; C:vacuole; IDA:TAIR.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IDA:UniProtKB.
DR   GO; GO:0010119; P:regulation of stomatal movement; IMP:TAIR.
DR   GO; GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.
DR   GO; GO:0009414; P:response to water deprivation; IMP:TAIR.
DR   InterPro; IPR008250; ATPase_P-typ_ATPase-assoc-dom.
DR   InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR   InterPro; IPR023300; ATPase_P-typ_cyto_domA.
DR   InterPro; IPR023299; ATPase_P-typ_cyto_domN.
DR   InterPro; IPR000695; ATPase_P-typ_H-transp.
DR   InterPro; IPR001757; ATPase_P-typ_ion-transptr.
DR   InterPro; IPR018303; ATPase_P-typ_P_site.
DR   InterPro; IPR006534; ATPase_P-typ_PM_proton-efflux.
DR   InterPro; IPR023298; ATPase_P-typ_TM_dom.
DR   InterPro; IPR005834; Dehalogen-like_hydro.
DR   InterPro; IPR023214; HAD-like_dom.
DR   Gene3D; G3DSA:2.70.150.10; ATPase_P-typ_cyto_domA; 2.
DR   Gene3D; G3DSA:3.40.1110.10; ATPase_P-typ_cyto_domN; 1.
DR   Gene3D; G3DSA:1.20.1110.10; ATPase_P-typ_TM_dom; 3.
DR   Pfam; PF00690; Cation_ATPase_N; 1.
DR   Pfam; PF00122; E1-E2_ATPase; 1.
DR   Pfam; PF00702; Hydrolase; 1.
DR   PRINTS; PR00119; CATATPASE.
DR   PRINTS; PR00120; HATPASE.
DR   SMART; SM00831; Cation_ATPase_N; 1.
DR   SUPFAM; SSF56784; HAD-like_dom; 1.
DR   TIGRFAMs; TIGR01647; ATPase-IIIA_H; 1.
DR   TIGRFAMs; TIGR01494; ATPase_P-type; 2.
DR   PROSITE; PS00154; ATPASE_E1_E2; 1.
DR   HOGENOMDNA; ARATH_2.PE1445; -.
KW   AT2G18960pg.C_scaffold_1320000031; AT2G18960.1.C_scaffold_1320000031;
KW   Q56WU9; Q570C2; AC003673; AK220788; AK221932; BT008692; M24107;
KW   Acetylation; ATP-binding; Cell membrane; Complete proteome;
KW   Hydrogen ion transport; Hydrolase; Ion transport; Magnesium; Membrane;
KW   Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   949 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSGLEDIKNE TVDLEKIPIE EVFQQLKCTR EGLTTQEGED RIVIFGPNKL EEKKESKILK
     FLGFMWNPLS WVMEAAALMA IALANGDNRP PDWQDFVGII CLLVINSTIS FIEENNAGNA
     AAALMAGLAP KTKVLRDGKW SEQEAAILVP GDIVSIKLGD IIPADARLLE GDPLKVDQSA
     LTGESLPVTK HPGQEVFSGS TCKQGEIEAV VIATGVHTFF GKAAHLVDST NQVGHFQKVL
     TSIGNFCICS IAIGIAIEIV VMYPIQHRKY RDGIDNLLVL LIGGIPIAMP TVLSVTMAIG
     SHRLSQQGAI TKRMTAIEEM AGMDVLCSDK TGTLTLNKLS VDKNLVEVFC KGVEKDQVLL
     FAAMASRVEN QDAIDAAMVG MLADPKEARA GIREVHFLPF NPVDKRTALT YIDSDGNWHR
     VSKGAPEQIL DLANARPDLR KKVLSCIDKY AERGLRSLAV ARQVVPEKTK ESPGGPWEFV
     GLLPLFDPPR HDSAETIRRA LNLGVNVKMI TGDQLAIGKE TGRRLGMGTN MYPSAALLGT
     DKDSNIASIP VEELIEKADG FAGVFPEHKY EIVKKLQERK HIVGMTGDGV NDAPALKKAD
     IGIAVADATD AARGASDIVL TEPGLSVIIS AVLTSRAIFQ RMKNYTIYAV SITIRIVFGF
     MLIALIWEFD FSAFMVLIIA ILNDGTIMTI SKDRVKPSPT PDSWKLKEIF ATGIVLGGYQ
     AIMSVIFFWA AHKTDFFSDK FGVRSIRDNN DELMGAVYLQ VSIISQALIF VTRSRSWSFV
     ERPGALLMIA FVIAQLVATL IAVYADWTFA KVKGIGWGWA GVIWIYSIVT YFPQDILKFA
     IRYILSGKAW ASLFDNRTAF TTKKDYGIGE REAQWAQAQR TLHGLQPKED VNIFPEKGSY
     RELSEIAEQA KRRAEIARLR ELHTLKGHVE SVAKLKGLDI DTAGHHYTV
//

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