(data stored in SCRATCH3701 zone)

HOGENOM6: ARCHD_1_PE6

ID   ARCHD_1_PE6                          STANDARD;      PRT;   854 AA.
AC   ARCHD_1_PE6; D7BLH5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (ARCHD_1.PE6).
GN   OrderedLocusNames=Arch_0006;
OS   ARCANOBACTERIUM HAEMOLYTICUM DSM 20595.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Actinomycineae; Actinomycetaceae; Arcanobacterium.
OX   NCBI_TaxID=644284;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ARCHD_1.PE6.
CC       Arcanobacterium haemolyticum DSM 20595 chromosome, complete genome.
CC       by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:D7BLH5_ARCHD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D7BLH5; -.
DR   EMBL; CP002045; ADH91774.1; -; Genomic_DNA.
DR   RefSeq; YP_003696393.1; NC_014218.1.
DR   GeneID; 9260558; -.
DR   GenomeReviews; CP002045_GR; Arch_0006.
DR   KEGG; ahe:Arch_0006; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ARCHD_1.PE6; -.
DR   PRODOM; ARCHD_1_PE6.
DR   SWISS-2DPAGE; ARCHD_1_PE6.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   854 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAEEMIQYNH GLIKDVDLQR EMETSYLDYA MSVIVGRALP DVRDGMKPVH RRVIYAMWDG
     GYRPDSSFSK SVKIVGDVMG NFHPHGDAAI YDTMVRLVQP WNMRYPLVAG QGNFGTAGDL
     GAAAPRYTEA RMAQLAVEMV RDINEETVDF VPNFDGSVQE PTVLTARFPN LLVNGSEGIA
     VGMATRIPPH NLREVAAGVQ WFLDNPEATR EELLDALLER VKGPDFPTGA TILGTKGIES
     MYRTGNGSIT QRAIVEVDEI NGRQCLVVTD LPFQVNPDRL LDKMVEGIKD GRLPGIADIR
     DESSGRAGQR IVIVLKKDAV AKVVLNNLYK HTQMQNNFPA NMLALVDGVP RTLSLDGFVR
     HWVNHQIEVI RRRTEFRLRK VLERLMILEG LVKALDALDE VIALIRRSPT VDEAREGLMK
     LLDINEIQAD HILAMQLRRL AALERQKILD ERDEKLALRD DYQDILAKPE RQRTIVSDEV
     GDIVAKFGDD RRTKILPFDG EVSDEDLIPE DDVVVTITRS GFVKRTKVSE YRAQHRGGKG
     IKGTTLRDDD IVEHFEVTST HDWQLFFTNM GRVYRIKGYE LPEGARDAKG QHIANLLAFQ
     PDERIASMVS IRSYDQADYL VLATEDGLVK KTRLADYDSA RTGGLIAVKL REREDGTMDR
     LVSARLLDDG ADVLLVSRGG QSLRFTADDA TLRPMGRATS GVTGMKFRGD DRLLAMDVVD
     EGAEVFVVTE GGYAKRTDIE QYRVQGRAGL GIKVANVVEA RGDLVGALIT HPGDEVMVIM
     ESGKVVRSAV DEVSLTGRNT QGVKFATPDK GDKIISIALN LEKQEDDEEV TTDVVEPTTE
     PVSEQDAETT TDVE
//

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