(data stored in ACNUC7421 zone)

HOGENOM: ASHGO_1_PE285

ID   ASHGO_1_PE285                        STANDARD;      PRT;   403 AA.
AC   ASHGO_1_PE285; Q75EI1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase;AltName:
DE   Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like
DE   protein; (ASHGO_1.PE285).
GN   Name=MRI1; OrderedLocusNames=AAR098W;
OS   ASHBYA GOSSYPII ATCC 10895.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ASHGO_1.PE285.
CC       Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-
CC       1056) chromosome I, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:MTNA_ASHGO
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q75EI1; -.
DR   EMBL; AE016814; AAS50463.1; -; Genomic_DNA.
DR   RefSeq; NP_982639.1; NM_207992.1.
DR   ProteinModelPortal; Q75EI1; -.
DR   SMR; Q75EI1; 1-205, 222-402.
DR   STRING; Q75EI1; -.
DR   GeneID; 4618528; -.
DR   GenomeReviews; AE016814_GR; AAR098W.
DR   KEGG; ago:AGOS_AAR098W; -.
DR   NMPDR; fig|33169.1.peg.284; -.
DR   AGD; AAR098W; -.
DR   eggNOG; fuNOG06631; -.
DR   OMA; EDGWKVI; -.
DR   OrthoDB; EOG4S1XGM; -.
DR   GO; GO:0005737; C:cytoplasm; ISS:RefGenome.
DR   GO; GO:0005634; C:nucleus; ISS:RefGenome.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; ISS:RefGenome.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; ISS:RefGenome.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; ASHGO_1.PE285; -.
KW   AAS50463.1003186affold_1320000031;
KW   Methylthioribose-1-phosphate isomerase ;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Methionine biosynthesis; Nucleus.
SQ   SEQUENCE   403 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSLQAIQFQR GDKSQVSVRV LDQLLLPYVS RYIPIQTVDD GFAVIRSMQV RGAPAIAIVG
     VLSVLVECQL LCNEDFVAVQ AFYDLSSYAA FGRTMRMRLA HLLGSRPTAV NLSHALRDVE
     RLLDSATSLS QFRDRMYDYA CELLDMDVAN NVRMGDNGAR FLLDALIAEG FDGSFAVLTI
     CNTGSLATAG YGTALGAIRS LWQHAEAGLT APKKQKASAC APRMTHVFPL ETRPYNQGSR
     LTAYELLHDA IPATLITDSS VAYRIQTSPV PIKAAFVGAD RIARNGDTAN KIGTLQLALV
     CRHFGIRFFV VAPRSTVDGT TAAGTDIPVE ERCPDEFRVV TGAAAGATGD PTTASVAIAP
     RDMPVWNPAF DVTPHAYIDA IVTETRVFTK DAAGNFDLDE LFT
//

If you have problems or comments...

PBIL Back to PBIL home page