(data stored in ACNUC7421 zone)

HOGENOM: ASPCL_53_PE2

ID   ASPCL_53_PE2                         STANDARD;      PRT;   385 AA.
AC   ASPCL_53_PE2; A1CGN9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase;AltName:
DE   Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like
DE   protein; (ASPCL_53.PE2).
GN   Name=mri1; ORFNames=ACLA_045090;
OS   ASPERGILLUS CLAVATUS.
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiales;
OC   mitosporic Trichocomacea; Aspergillus.
OX   NCBI_TaxID=5057;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ASPCL_53.PE2.
CC       Aspergillus clavatus contig 293 CADRE full sequence 1..2412819 annotate
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:MTNA_ASPCL
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Aspergillus_clavatus;CADACLAG00004746;CADACLAT00004746;CADACLAP00004645.
DR   EMBL; DS027054; - ;
DR   UniProtKB/Swiss-Prot; A1CGN9; -.
DR   EMBL; DS027054; EAW10044.1; -; Genomic_DNA.
DR   RefSeq; XP_001271470.1; XM_001271469.1.
DR   ProteinModelPortal; A1CGN9; -.
DR   STRING; A1CGN9; -.
DR   EnsemblFungi; CADACLAT00004746; CADACLAP00004645; CADACLAG00004746.
DR   GeneID; 4704247; -.
DR   KEGG; act:ACLA_045090; -.
DR   GeneTree; EFGT00050000003245; -.
DR   OrthoDB; EOG4S1XGM; -.
DR   PhylomeDB; A1CGN9; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; ASPCL_53.PE2; -.
KW   CADACLAG00004746affold_1320000031; CADACLAP00004645affold_1320000031;
KW   DS027054;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Methionine biosynthesis; Nucleus.
SQ   SEQUENCE   385 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTLEAIRYST GKLVIIDQLQ LPYVEKYIEV PTSKDAWHAI KKMRVRGAPA IAIVAALALA
     SELHTLMAHD KLSNRAEEVR LFIQEKLDYL VSSRPTAVNL SDAARKLAAH VSDHAEMPNS
     TGRAVAEAFI QAAEEMLAKD LKDNTNIGKY GAEWIIRNAL AGGRSKATIL THCNTGSLAT
     SGYGTALGVI RALASKNALA YAYCTETRPY NQGSRLTAYE LVHENLPATL VTDSMVAALL
     AKAEAAVDAI VVGADRVAAN GDTANKIGTY ALAVLAKFHG VKFLVAAPLT TIDRSTKSGA
     DIVIEERPAS EVTTIKGAVE TESSCDRIKL ETVRIAAEGI HVWNPAFDVT PSALIDAIIT
     ERGVVERGTD GRYNFDGIFE DHSAF
//

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