(data stored in ACNUC7421 zone)

HOGENOM: AZOS1_1_PE1009

ID   AZOS1_1_PE1009                       STANDARD;      PRT;   454 AA.
AC   AZOS1_1_PE1009; D3NTB8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Serine hydroxymethyltransferase; EC=2.1.2 1;
DE   (AZOS1_1.PE1009).
GN   Name=glyA; OrderedLocusNames=AZL_010090;
OS   AZOSPIRILLUM SP. B510.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Azospirillum.
OX   NCBI_TaxID=137722;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AZOS1_1.PE1009.
CC       Azospirillum sp. B510 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:D3NTB8_AZOS1
CC   -!- FUNCTION: Interconversion of serine and glycine (By similarity).
CC   -!- CATALYTIC ACTIVITY: 5,10-methylenetetrahydrofolate + glycine +
CC       H(2)O = tetrahydrofolate + L-serine.
CC   -!- COFACTOR: Pyridoxal phosphate (By similarity).
CC   -!- PATHWAY: One-carbon metabolism; tetrahydrofolate pathway.
CC   -!- SIMILARITY: Belongs to the SHMT family.
CC   -!- GENE_FAMILY: HOG000239404 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D3NTB8; -.
DR   EMBL; AP010946; BAI71647.1; -; Genomic_DNA.
DR   RefSeq; YP_003448191.1; NC_013854.1.
DR   ProteinModelPortal; D3NTB8; -.
DR   GeneID; 8791356; -.
DR   GenomeReviews; AP010946_GR; AZL_010090.
DR   KEGG; azl:AZL_010090; -.
DR   GO; GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006544; P:glycine metabolic process; IEA:InterPro.
DR   GO; GO:0006563; P:L-serine metabolic process; IEA:InterPro.
DR   HAMAP; MF_00051_B; SHMT_B; 1; -.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase_major_dom.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_major_sub2.
DR   InterPro; IPR001085; Ser_HO-MeTrfase.
DR   InterPro; IPR019798; Ser_HO-MeTrfase_PLP_BS.
DR   Gene3D; G3DSA:3.40.640.10; PyrdxlP-dep_Trfase_major_sub1; 1.
DR   Gene3D; G3DSA:3.90.1150.10; PyrdxlP-dep_Trfase_major_sub2; 1.
DR   PANTHER; PTHR11680; Gly_HO-Metrfase; 1.
DR   Pfam; PF00464; SHMT; 1.
DR   PIRSF; PIRSF000412; SHMT; 1.
DR   SUPFAM; SSF53383; PyrdxlP-dep_Trfase_major; 1.
DR   PROSITE; PS00096; SHMT; 1.
DR   HOGENOMDNA; AZOS1_1.PE1009; -.
KW   glycine hydroxymethyltransferase;
KW   Complete proteome; Methyltransferase; One-carbon metabolism;
KW   Pyridoxal phosphate; Transferase.
SQ   SEQUENCE   454 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTAGDHVSGR RHALSIEEPS AMTSSNTAEI GRFFAASLAE TDPELARAVR DELVRQQEQI
     ELIASENIVS QAVLEAQGSV LTNKYAEGYP GKRYYGGCEF VDVAETLAIE RACKLFGCGF
     ANVQPNSGSQ ANQAVLLALL QPGDCVLGMS LAAGGHLTHG AAPNMSGKWF KAVQYGVRKD
     DHLIDFDQVE ALAREHKPKL IIAGGSAYPR VLDYQRFRAI ADEVGAIFMV DIAHYAGLIA
     GGVYPNPFPY ADVVTTTTHK TLRGPRGGMV LTNKEDIAKK INSAVFPGLQ GGPLMHVIAG
     KAVAFAEALR PEFKTYAQAV VDNAQVLAKT LIAGGLDIVS GGTDSHIVLV DLRPKNLTGK
     AAEASLEHAG MTCNKNGVPF DPQKPMITSG VRLGSPAATT RGFGTAEFRQ VGEMIVETLD
     GLAASNSGDN AAVEASVRER VRGLCRQFPI YPTL
//

If you have problems or comments...

PBIL Back to PBIL home page