(data stored in SCRATCH3701 zone)

HOGENOM6: AZOSB_1_PE1065

ID   AZOSB_1_PE1065                       STANDARD;      PRT;   877 AA.
AC   AZOSB_1_PE1065; A1K4C8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA topoisomerase (AZOSB_1.PE1065) (ATP-hydrolysing);
DE   EC=5.99.1 3; .
GN   Name=gyrA; OrderedLocusNames=azo1066;
OS   AZOARCUS SP. BH72.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Rhodocyclaceae; Azoarcus.
OX   NCBI_TaxID=62928;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AZOSB_1.PE1065.
CC       Azoarcus sp. BH72 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:A1K4C8_AZOSB
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A1K4C8; -.
DR   EMBL; AM406670; CAL93683.1; -; Genomic_DNA.
DR   RefSeq; YP_932570.1; NC_008702.1.
DR   ProteinModelPortal; A1K4C8; -.
DR   SMR; A1K4C8; 30-522, 536-843.
DR   STRING; A1K4C8; -.
DR   GeneID; 4606680; -.
DR   GenomeReviews; AM406670_GR; azo1066.
DR   KEGG; azo:azo1066; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; A1K4C8; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; AZOSB_1.PE1065; -.
DR   PRODOM; AZOSB_1_PE1065.
DR   SWISS-2DPAGE; AZOSB_1_PE1065.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   877 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTQFAKETLP ISLEEEMRHS YLDYAMSVIV GRALPDARDG LKPVHRRVLY AMHELSNDWN
     RAYKKSARIV GDVIGKYHPH GDSAVYDTIV RMAQDFSLRY MLVDGQGNFG SVDGDNAAAM
     RYTEIRMARI GHELLADIDK ETVDFGPNYD GSEKEPLILP ARIPNLLING SSGIAVGMAT
     NIPPHNLGEV VDACLKLLED PETDLEALIE IVKAPDFPTA GLIYGLHGVH EGYRTGRGRV
     VMRARTHIEP IGKNSDREAI IVDELPYQVN KRTLLERIAE LVNEKKVEGI SEIRDESDKS
     GMRVVIELKR NEMPEVVLNN LYKHTQLQDT FGMNMVALVD GKPRLLNLKQ MLVCFLEHRR
     EVVTRRTIFE LKKARDRGHI LEGLAVALSN VDEIIALIKA APTPADAKRG LMERTWRSPL
     VEEMLSRALA DSYRPEGLDP EFGFSAQGYK LSDAQAQAIL ELRLQRLTGL EQDKIVGEYR
     EVMDLITDLL DILARPERIT AIIVEELTAI RNQFGDPRRS EIVLSTAEIN IEDLITPEDM
     VVTLSHTGYF KRQPLADYRA QRRGGRGKQA TSMKDEDFID HLFVANTHDT VLCFSSRGRA
     YWLKVYEVPE GTRNSRGKPI VNLFPLIEGE KITAVLPVQT FDEEHFVFMA TSEGTVKKTA
     LTAFANPRKA GIIAVNLDDG DHLIGVAITD GECDVMLFSD AGKAVRFAES DVRPMGREAR
     GVRGMTLEDG QRVIAMLVAK GETQSVLTAT ENGYGKRTPV AEYTRHGRGT KGMIAIQTSD
     RNGKLVGAVL VDPTDEVMLI STGAVLIRTK VQDIRELGRA TQGVTLINLD EGTYLAGIEK
     VAESGAEADE LVEGGEEGAA DGEDAGAPGA AGEGEQE
//

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