(data stored in ACNUC4932 zone)

HOVERGEN: B0ZTH9_RAT

ID   B0ZTH9_RAT              Unreviewed;       372 AA.
AC   B0ZTH9;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   03-NOV-2009, entry version 9.
DE   SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase-4 transcript variant 3;
DE            EC=2.7.1.105;
DE            EC=3.1.3.46;
GN   Name=Pfkfb4;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=W; TISSUE=Lung;
RA   Minchenko D.O., Kovtun O.O., Minchenko O.H., Byts J.V.;
RT   "A family of alternative splice variants of 6-phosphofructo-2-
RT   kinase/fructose-2,6-bisphosphatase-4 mRNA.";
RL   (In) Unknown A. (eds.);
RL   SCIENTIFIC BULLETIN OF NATIONAL O.O. BOGOMOLETZ MEDICAL UNIVERSITY,
RL   pp.72-78, National O.O. Bogomoletz Medical University, Ukraine (2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=W; TISSUE=Lung;
RA   Minchenko D.O., Paustovsky Y.O., Mykhalchenko V.G., Yavorovsky O.P.,
RA   Tsuchihara K.O., Esumi H., Minchenko O.H.;
RT   "Unusual alternative splice variants of rat 6-phosphofructo-2-
RT   kinase/fructose-2,6-bisphosphatase-4 mRNA.";
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
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CC   -!- GENE_FAMILY: HBG005628 [ FAMILY / ALN / TREE ]
DR   EMBL; EU404102; ABZ79896.1; -; mRNA.
DR   IPI; IPI00230820; -.
DR   UniGene; Rn.90092; -.
DR   STRING; B0ZTH9; -.
DR   Ensembl; ENSRNOT00000028039; ENSRNOP00000028039; ENSRNOG00000020656; Rattus norvegicus.
DR   Ensembl; ENSRNOT00000037662; ENSRNOP00000033343; ENSRNOG00000020656; Rattus norvegicus.
DR   Ensembl; ENSRNOT00000066305; ENSRNOP00000061383; ENSRNOG00000020656; Rattus norvegicus.
DR   Ensembl; ENSRNOT00000067241; ENSRNOP00000060072; ENSRNOG00000020656; Rattus norvegicus.
DR   Genevestigator; B0ZTH9; -.
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:EC.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase act...; IEA:EC.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   InterPro; IPR003094; 6Pfruct_kin.
DR   InterPro; IPR013079; 6Phosfructo_kin.
DR   InterPro; IPR016260; Bifunct_6PFK/fruc_bisP_Ptase.
DR   InterPro; IPR001345; PG/BPGM_mutase_AS.
DR   InterPro; IPR013078; PG_mutase.
DR   PANTHER; PTHR10606; 6Pfruct_kin; 1.
DR   Pfam; PF01591; 6PF2K; 1.
DR   Pfam; PF00300; PGAM; 1.
DR   PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR   PRINTS; PR00991; 6PFRUCTKNASE.
DR   SMART; SM00855; PGAM; 1.
DR   PROSITE; PS00175; PG_MUTASE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; B0ZTH9.
DR   SWISS-2DPAGE; B0ZTH9.
KW   Hydrolase; Kinase; Transferase.
SQ   SEQUENCE   372 AA;  43178 MW;  383565D6A97057E5 CRC64;
     MASPRELTQN PLKKIWMPYS NGRPALHASQ RGVCMTNCPT LIVMVGLPAR GKTYISKKLT
     RYLNWIGVPT REFNVGQYRR DMVKTYKSFE FFLPDNEEGL KIRKQCALAA LNDVRKFLSE
     EGGHVAVFDA TNTTRERRAM IFNFGEQNGY KTFFVESICV DPEVIAANIV QVKLGSPDYV
     NRDSDEATED FMRRIECYEN SYESLDEEQD RDLSYIKIMD VGQSYVVNRV ADHIQSRIVY
     YLMNIHVTPR SIYLCRHGES ELNLKGRIGG DPGLSPRGRE FSKHLAQFIS DQNIKDLKVW
     TSQMKRTIQT AEALSVPYEQ WKVLNEIDAG VCEEMTYEEI QDHYPLEFAL RDQDKYRYRY
     PKGEVVKWSP YS
//

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