(data stored in ACNUC4932 zone)

HOVERGEN: B2Z894_MOUSE

ID   B2Z894_MOUSE            Unreviewed;       374 AA.
AC   B2Z894;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   03-NOV-2009, entry version 13.
DE   SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 variant 6;
DE            EC=2.7.1.105;
GN   Name=Pfkfb2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6; TISSUE=Brain;
RX   PubMed=14623077; DOI=10.1016/S0014-5793(03)01179-7;
RA   Minchenko O.H., Opentanova I.L., Caro J.;
RT   "Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-
RT   bisphosphatase gene family (PFKFB-1-4) expression in vivo.";
RL   FEBS Lett. 554:264-270(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C57BL/6; TISSUE=Brain;
RA   Minchenko D.O., Tsuchihara K., Moenner M., Bikfalvi A.,
RA   Komisarenko S.V., Esumi H., Caro J., Minchenko O.;
RT   "Unique alternative splice variants of mouse 6-phosphofructo-2-
RT   kinase/fructose-2,6-bisphosphatase-2.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
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CC   -!- GENE_FAMILY: HBG005628 [ FAMILY / ALN / TREE ]
DR   EMBL; EU616669; ACC97557.1; -; mRNA.
DR   IPI; IPI00938544; -.
DR   UniGene; Mm.249861; -.
DR   STRING; B2Z894; -.
DR   Ensembl; ENSMUST00000066863; ENSMUSP00000066426; ENSMUSG00000026409; Mus musculus.
DR   MGI; MGI:107815; Pfkfb2.
DR   Bgee; B2Z894; -.
DR   Genevestigator; B2Z894; -.
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:EC.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   InterPro; IPR003094; 6Pfruct_kin.
DR   InterPro; IPR013079; 6Phosfructo_kin.
DR   InterPro; IPR016260; Bifunct_6PFK/fruc_bisP_Ptase.
DR   InterPro; IPR001345; PG/BPGM_mutase_AS.
DR   InterPro; IPR013078; PG_mutase.
DR   PANTHER; PTHR10606; 6Pfruct_kin; 1.
DR   Pfam; PF01591; 6PF2K; 1.
DR   Pfam; PF00300; PGAM; 1.
DR   PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR   PRINTS; PR00991; 6PFRUCTKNASE.
DR   SMART; SM00855; PGAM; 1.
DR   PROSITE; PS00175; PG_MUTASE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; B2Z894.
DR   SWISS-2DPAGE; B2Z894.
KW   Kinase; Transferase.
SQ   SEQUENCE   374 AA;  43536 MW;  65052D474A61B032 CRC64;
     MSENSTFSPE DCNSSYKPHA SNLRRAGKTC SWASYMTNSP TLIVMIGLPA RGKTYVSKKL
     TRYLNWIGVP TKVFNLGVYR REAVKSYQSY DFFRHDNEEA MKIRKQCALV ALEDVKAYFT
     EESGQIAVFD ATNTTRERRD MILNFAKQNA FKVFFVESVC DDPDVIAANI LEVKVSSPDY
     PERNRENVME DFLKRIECYK VTYQPLDPDN YDKDLSFIKV INVGQRFLVN RVQDYIQSKI
     VYYLMNIHVH PRTIYLCRHG ESEFNLLGKI GGDSGLSVRG KQFAHALKKF LEEQEIQDLK
     VWTSQLKRTI QTAESLGVTY EQWKILNEID AGVCEEMTYS EIEQRYPEEF ALRDQEKYLY
     RYPGGEVAKW KQLL
//

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