(data stored in ACNUC4932 zone)

HOVERGEN: B7Z8A0_HUMAN

ID   B7Z8A0_HUMAN            Unreviewed;       500 AA.
AC   B7Z8A0;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   03-NOV-2009, entry version 7.
DE   SubName: Full=cDNA FLJ54727, highly similar to 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis;
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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CC   -!- GENE_FAMILY: HBG005628 [ FAMILY / ALN / TREE ]
DR   EMBL; AK303039; BAH13886.1; -; mRNA.
DR   IPI; IPI00004511; -.
DR   Ensembl; ENST00000317350; ENSP00000369105; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000358499; ENSP00000351288; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000360521; ENSP00000353712; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000379775; ENSP00000369100; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000379781; ENSP00000369107; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000379782; ENSP00000369108; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000379784; ENSP00000369110; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000379785; ENSP00000369111; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000379789; ENSP00000369115; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000414237; ENSP00000416677; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000441697; ENSP00000404995; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000444592; ENSP00000402055; ENSG00000170525; Homo sapiens.
DR   Ensembl; ENST00000450232; ENSP00000390285; ENSG00000170525; Homo sapiens.
DR   HGNC; HGNC:8874; PFKFB3.
DR   Bgee; B7Z8A0; -.
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   InterPro; IPR003094; 6Pfruct_kin.
DR   InterPro; IPR013079; 6Phosfructo_kin.
DR   InterPro; IPR016260; Bifunct_6PFK/fruc_bisP_Ptase.
DR   InterPro; IPR001345; PG/BPGM_mutase_AS.
DR   InterPro; IPR013078; PG_mutase.
DR   PANTHER; PTHR10606; 6Pfruct_kin; 1.
DR   Pfam; PF01591; 6PF2K; 1.
DR   Pfam; PF00300; PGAM; 1.
DR   PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR   PRINTS; PR00991; 6PFRUCTKNASE.
DR   SMART; SM00855; PGAM; 1.
DR   PROSITE; PS00175; PG_MUTASE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; B7Z8A0.
DR   SWISS-2DPAGE; B7Z8A0.
KW   Kinase.
SQ   SEQUENCE   500 AA;  57271 MW;  0F9292497C607C1C CRC64;
     MPFRKACGPK LTNSPTVIVM VGLPARGKTY ISKKLTRYLN WIGVPTKVFN VGEYRREAVK
     QYSSYNFFRP DNEEAMKVRK QCALAALRDV KSYLAKEGGQ IAVFDATNTT RERRHMILHF
     AKENDFKAFF IESVCDDPTV VASNIMEVKI SSPDYKDCNS AEAMDDFMKR ISCYEASYQP
     LDPDKCDRDL SLIKVIDVGR RFLVNRVQDH IQSRIVYYLM NIHVQPRTIY LCRHGENEHN
     PQGRIGGDSG LSSRGKKFAS ALSKFVEEQN LKDLRVWTSQ LKSTIQTAEA LRLPYEQWKA
     LNEIDAGVCE ELTYEEIRDT YPEEYALREQ DKYYYRYPTG ESYQDLVQRL EPVIMELERQ
     ENVLVICHQA VLRCLLAYFL DKSAEEMPYL KCPLHTVLKL TPVAYGCRVE SIYLNVESVC
     THRERSEDAK KGPNPLMRRN SVTPLASPEP TKKPRINSFE EHVASTSAAL PSCLPPEVPT
     QLPGQNMKGS RSSADSSRKH
//

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