(data stored in SCRATCH3701 zone)

HOGENOM6: BACFN_1_PE2373

ID   BACFN_1_PE2373                       STANDARD;      PRT;   845 AA.
AC   BACFN_1_PE2373; Q5LCH2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase A subunit; (BACFN_1.PE2373).
GN   Name=gyrA; OrderedLocusNames=BF2493; ORFNames=BF9343_2412;
OS   BACTEROIDES FRAGILIS NCTC 9343.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=272559;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BACFN_1.PE2373.
CC       Bacteroides fragilis NCTC 9343 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q5LCH2_BACFN
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5LCH2; -.
DR   EMBL; CR626927; CAH08193.1; -; Genomic_DNA.
DR   RefSeq; YP_212117.1; NC_003228.3.
DR   ProteinModelPortal; Q5LCH2; -.
DR   SMR; Q5LCH2; 29-484.
DR   STRING; Q5LCH2; -.
DR   GeneID; 3289212; -.
DR   GenomeReviews; CR626927_GR; BF2493.
DR   KEGG; bfs:BF2493; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BACFN_1.PE2373; -.
DR   PRODOM; BACFN_1_PE2373.
DR   SWISS-2DPAGE; BACFN_1_PE2373.
KW   DNA gyrase A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   845 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLEQDRIIKI NIEEEMKSSY IDYSMSVIVS RALPDVRDGF KPVHRRILYG MMELGNTSDK
     PYKKSARIVG EVLGKYHPHG DSSVYFAMVR MAQEWAMRYP LVDGQGNFGS VDGDSPAAMR
     YTEARLNKLG EEMMQDLYKE TVDFEPNFDN TLMEPKVMPT RIPNLLVNGA SGIAVGMATN
     MPPHNLSEVI DACEAYLDNK DVTVEELMEY VKAPDFPTGG YIYGISGVRE AYLTGRGRVV
     MRAKAEIESG QTHDKIVVTE IPYNVNKAEL IKAIADLVNE KRIEGISNAN DESDREGMRI
     VIDIKRDANA SVVLNKLYKM TALQTSFGVN NVALVNGRPK MLNLRDLIVY FVEHRHDVVI
     RRTQFDLRKA KERAHILEGL IIASDNIDEV IRIIRAAKTP NDAISGLMER FNLSEIQARA
     IVEMRLRQLT GLMQDQLHAE YEEVMKQIAY LESILADDEV CRKVIKDELL EVRAKYGDER
     RSEIVYSSEE FNPEDFYADD QMIITISHMG YIKRTPLTEF RAQNRGGVGS KGTETRDEDF
     VEHIYPATMH NTMMFFTQKG KCYWLKVYEI PEGTKNSKGR AIQNLLNIDS DDAVNAYLRV
     KSLNDQEYIN SHYVLFCTKN GVIKKTSLEQ YSRPRQNGVN AITIREDDRV IEVRMTNGNN
     EIIIANRNGR AIRFHEAAVR VMGRTATGVR GITLDDDGQD EVIGMICIKD LETESVMVVS
     EQGYGKRSDI EDYRKTNRGG KGVKTMNITE KTGKLVTIKS VTDENDLMII NKSGITIRLK
     VADVRIMGRA TQGVRLINLE KRNDQIGSVC KVTSESLEDE VPEEEREGNI PSDPETNTPV
     NETEE
//

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