(data stored in SCRATCH3701 zone)

HOGENOM6: BACP2_1_PE7

ID   BACP2_1_PE7                          STANDARD;      PRT;   839 AA.
AC   BACP2_1_PE7; A8F8Z0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA topoisomerase (BACP2_1.PE7) (ATP-hydrolyzing) subunit
DE   A; EC=5.99.1 3; .
GN   Name=gyrA; OrderedLocusNames=BPUM_0007;
OS   BACILLUS PUMILUS SAFR-032.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=315750;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BACP2_1.PE7.
CC       Bacillus pumilus SAFR-032, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A8F8Z0_BACP2
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A8F8Z0; -.
DR   EMBL; CP000813; ABV60707.1; -; Genomic_DNA.
DR   RefSeq; YP_001485267.1; NC_009848.1.
DR   ProteinModelPortal; A8F8Z0; -.
DR   SMR; A8F8Z0; 31-487.
DR   STRING; A8F8Z0; -.
DR   EnsemblBacteria; EBBACT00000063679; EBBACP00000062012; EBBACG00000063670.
DR   GeneID; 5619217; -.
DR   GenomeReviews; CP000813_GR; BPUM_0007.
DR   KEGG; bpu:BPUM_0007; -.
DR   eggNOG; COG0188; -.
DR   GeneTree; EBGT00050000002933; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BACP2_1.PE7; -.
DR   PRODOM; BACP2_1_PE7.
DR   SWISS-2DPAGE; BACP2_1_PE7.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   839 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSEQHTPNVR EVNISQEMRT SFLDYAMSVI VSRALPDVRD GLKPVHRRIL YAMNDLGMTS
     DKPFKKSARI VGEVIGKYHP HGDSAVYEAM VRMAQDFNYR YMLVDGHGNF GSVDGDGAAA
     MRYTEARLSK ISMEILRDIT KDTIDYQDNY DGSEREPMVM PARFPNLLVN GATGIAVGMA
     TNIPPHQLGE VIDGVLAISQ NPEMTTQELM DIIPGPDFPT AGQIIGRSGI RKAYETGRGS
     ITLRAKSNIE ETSSGKQRIV INEIPYQVNK ARLIEKIADL VRDKKIDGIT DLRDESDRNG
     MRIVIELRRD ANVHVLLNNL YKQTTLQTSF GINLLALVDG QPKVLSLKQC LEYYLEHQKV
     IIRRRTAYEL RKAEARAHIL EGLRIALDHL DEVIALIRGS QTAEIARNGL MENYSLSEKQ
     AQAILDMRLQ RLTGLEREKI EDEYKGLVDL IAELKAILAD NEKVLEIIRE ELTEIKERFN
     DTRRTEIVTA GIETIEDEDL IPVENIVITL THNGYIKRLP ASTYRSQKRG GKGVQGMGTN
     EDDFVEQLIS TSTHDTILFF SNKGKVYRAK GYEIPEFGRT AKGIPIINLL EVEKGEWINA
     IIPVSEFDEN SYLFFTTRHG VSKRTTLSQF ANIRNNGLIA LSLRDEDELM AVRLTNGEKQ
     IIIGTKKGML IRFDETDVRE MGRTAAGVKG ITLSEDDIVV GMEILEPDAN VLIVTEKGYG
     KLTPEKEYRV QSRGGKGLKT CKITDNNGPL VAVKATNAEA EEDLMIITGS GVIIRMAVSD
     ISTTGRVTQG VRLIRLGDEE HVATVALVEQ SPEDDEDNEE NVENIENIEN IESDQEQSE
//

If you have problems or comments...

PBIL Back to PBIL home page