(data stored in ACNUC7421 zone)

HOGENOM: BASUB1_1_PE1

ID   BASUB1_1_PE1                         STANDARD;      PRT;   446 AA.
AC   BASUB1_1_PE1; P05648;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (BASUB1_1.PE1).
GN   Name=dnaA; Synonyms=dnaH; OrderedLocusNames=BSU00010;
OS   BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BASUB1_1.PE1.
CC       Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:DNAA_BACSU
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. DnaA can inhibit its own gene expression as well as
CC       that of other genes.
CC   -!- SUBUNIT: Some 20 DnaA protein molecules bind their sites in oriC.
CC   -!- INTERACTION:
CC       P37522:soj; NbExp=2; IntAct=EBI-2014722, EBI-2014674;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P05648; -.
DR   EMBL; X02369; CAA26217.1; -; Genomic_DNA.
DR   EMBL; D26185; BAA05237.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB11777.1; -; Genomic_DNA.
DR   EMBL; X12778; CAA31269.1; -; Genomic_DNA.
DR   EMBL; X12779; CAA31270.1; -; Genomic_DNA.
DR   PIR; A22930; IQBSOC.
DR   RefSeq; NP_387882.1; NC_000964.3.
DR   ProteinModelPortal; P05648; -.
DR   SMR; P05648; 5-83, 109-446.
DR   IntAct; P05648; 1.
DR   EnsemblBacteria; EBBACT00000003301; EBBACP00000003301; EBBACG00000003294.
DR   GeneID; 939978; -.
DR   GenomeReviews; AL009126_GR; BSU00010.
DR   KEGG; bsu:BSU00010; -.
DR   NMPDR; fig|224308.1.peg.1; -.
DR   GenoList; BSU00010; -.
DR   GeneTree; EBGT00050000000588; -.
DR   OMA; IQRVVGQ; -.
DR   PhylomeDB; P05648; -.
DR   ProtClustDB; PRK00149; -.
DR   BioCyc; BSUB:BSU00010-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; BASUB1_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
SQ   SEQUENCE   446 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MENILDLWNQ ALAQIEKKLS KPSFETWMKS TKAHSLQGDT LTITAPNEFA RDWLESRYLH
     LIADTIYELT GEELSIKFVI PQNQDVEDFM PKPQVKKAVK EDTSDFPQNM LNPKYTFDTF
     VIGSGNRFAH AASLAVAEAP AKAYNPLFIY GGVGLGKTHL MHAIGHYVID HNPSAKVVYL
     SSEKFTNEFI NSIRDNKAVD FRNRYRNVDV LLIDDIQFLA GKEQTQEEFF HTFNTLHEES
     KQIVISSDRP PKEIPTLEDR LRSRFEWGLI TDITPPDLET RIAILRKKAK AEGLDIPNEV
     MLYIANQIDS NIRELEGALI RVVAYSSLIN KDINADLAAE ALKDIIPSSK PKVITIKEIQ
     RVVGQQFNIK LEDFKAKKRT KSVAFPRQIA MYLSREMTDS SLPKIGEEFG GRDHTTVIHA
     HEKISKLLAD DEQLQQHVKE IKEQLK
//

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