(data stored in ACNUC7421 zone)

HOGENOM: BASUB1_1_PE10

ID   BASUB1_1_PE10                        STANDARD;      PRT;   443 AA.
AC   BASUB1_1_PE10; P08750;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=D-alanyl-D-alanine carboxypeptidase dacA; Short=CPase;
DE   Short=DD-carboxypeptidase; Short=DD-peptidase; EC=3.4.16 4;AltName:
DE   Full=Penicillin-binding protein 5; Short=PBP-5;Flags: Precursor;
DE   (BASUB1_1.PE10).
GN   Name=dacA; OrderedLocusNames=BSU00100;
OS   BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BASUB1_1.PE10.
CC       Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:DACA_BACSU
CC   -!- FUNCTION: Removes C-terminal D-alanyl residues from sugar-peptide
CC       cell wall precursors.
CC   -!- CATALYTIC ACTIVITY: Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-
CC       D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are
CC       N-acyl substituents of D-alanine.
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall.
CC   -!- SIMILARITY: Belongs to the peptidase S11 family.
CC   -!- GENE_FAMILY: HOG000086625 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P08750; -.
DR   EMBL; D26185; BAA05246.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB11786.1; -; Genomic_DNA.
DR   EMBL; M13766; AAA22375.1; -; Genomic_DNA.
DR   PIR; S66040; S66040.
DR   RefSeq; NP_387891.1; NC_000964.3.
DR   ProteinModelPortal; P08750; -.
DR   SMR; P08750; 36-412.
DR   MEROPS; S11.001; -.
DR   EnsemblBacteria; EBBACT00000000263; EBBACP00000000263; EBBACG00000000263.
DR   GeneID; 940000; -.
DR   GenomeReviews; AL009126_GR; BSU00100.
DR   KEGG; bsu:BSU00100; -.
DR   NMPDR; fig|224308.1.peg.10; -.
DR   GenoList; BSU00100; -.
DR   GeneTree; EBGT00070000031765; -.
DR   OMA; TMRSIGG; -.
DR   ProtClustDB; CLSK886544; -.
DR   BioCyc; BSUB:BSU00100-MON; -.
DR   GO; GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:EC.
DR   GO; GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR015956; Peniciliin-bd_prot-assoc.
DR   InterPro; IPR018044; Peptidase_S11.
DR   InterPro; IPR012907; Peptidase_S11_C.
DR   InterPro; IPR001967; Peptidase_S11_N.
DR   Gene3D; G3DSA:3.40.710.10; G3DSA:3.40.710.10; 1.
DR   Gene3D; G3DSA:2.60.410.10; Peptidase_S11_C; 1.
DR   Pfam; PF07943; PBP5_C; 1.
DR   Pfam; PF00768; Peptidase_S11; 1.
DR   PRINTS; PR00725; DADACBPTASE1.
DR   SMART; SM00936; PBP5_C; 1.
DR   SUPFAM; SSF56601; PBP_transp_fold; 1.
DR   SUPFAM; SSF69189; Peniciliin-bd_prot-assoc; 1.
DR   HOGENOMDNA; BASUB1_1.PE10; -.
KW   Carboxypeptidase; Cell shape; Cell wall;
KW   Cell wall biogenesis/degradation; Complete proteome;
KW   Direct protein sequencing; Hydrolase; Peptidoglycan synthesis;
KW   Protease; Reference proteome; Secreted; Signal.
SQ   SEQUENCE   443 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNIKKCKQLL MSLVVLTLAV TCLAPMSKAK AASDPIDINA SAAIMIEASS GKILYSKNAD
     KRLPIASMTK MMTEYLLLEA IDQGKVKWDQ TYTPDDYVYE ISQDNSLSNV PLRKDGKYTV
     KELYQATAIY SANAAAIAIA EIVAGSETKF VEKMNAKAKE LGLTDYKFVN ATGLENKDLH
     GHQPEGTSVN EESEVSAKDM AVLADHLITD YPEILETSSI AKTKFREGTD DEMDMPNWNF
     MLKGLVSEYK KATVDGLKTG STDSAGSCFT GTAERNGMRV ITVVLNAKGN LHTGRFDETK
     KMFDYAFDNF SMKEIYAEGD QVKGHKTISV DKGKEKEVGI VTNKAFSLPV KNGEEKNYKA
     KVTLNKDNLT APVKKGTKVG KLTAEYTGDE KDYGFLNSDL AGVDLVTKEN VEKANWFVLT
     MRSIGGFFAG IWGSIVDTVT GWF
//

If you have problems or comments...

PBIL Back to PBIL home page