(data stored in ACNUC1104 zone)

HOGENOM: BASUB1_1_PE3819

ID   BASUB1_1_PE3819                      STANDARD;      PRT;   466 AA.
AC   BASUB1_1_PE3819; Q00538;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylenomycin A resistance protein;AltName: Full=MMR
DE   peptide; (BASUB1_1.PE3819).
GN   Name=mmr; OrderedLocusNames=BSU37570;
OS   BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BASUB1_1.PE3819.
CC       Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:MMR_BACSU
CC   -!- FUNCTION: Resistance to the epoxide antibiotic methylenomycin.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. EmrB
CC       family.
CC   -!- GENE_FAMILY: HOG000239124 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q00538; -.
DR   EMBL; X66121; CAA46908.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15784.1; -; Genomic_DNA.
DR   PIR; I40493; YTBSMA.
DR   RefSeq; NP_391637.1; NC_000964.3.
DR   ProteinModelPortal; Q00538; -.
DR   TCDB; 2.A.1.3.10; major facilitator superfamily (MFS).
DR   EnsemblBacteria; EBBACT00000001061; EBBACP00000001061; EBBACG00000001059.
DR   GeneID; 937101; -.
DR   GenomeReviews; AL009126_GR; BSU37570.
DR   KEGG; bsu:BSU37570; -.
DR   NMPDR; fig|224308.1.peg.3763; -.
DR   GenoList; BSU37570; -.
DR   GeneTree; EBGT00070000031968; -.
DR   OMA; MATLDVT; -.
DR   PhylomeDB; Q00538; -.
DR   BioCyc; BSUB:BSU37570-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR004638; Drug-R_transpt_efflux_EmrB.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR016196; MFS_dom_general_subst_transpt.
DR   Pfam; PF07690; MFS_1; 2.
DR   SUPFAM; SSF103473; MFS_gen_substrate_transporter; 2.
DR   TIGRFAMs; TIGR00711; Efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   HOGENOMDNA; BASUB1_1.PE3819; -.
KW   toxic compound efflux transporter;
KW   Antibiotic resistance; Cell membrane; Complete proteome; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   466 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKNSGSIQES TSSTGISVLI VLALGFLMAT LDVTVVNVAM ADMKNTLSMS LSGVTWVVDG
     YILTFASLLL AGGALADRFG SKTIYILGLA VFVMASCLCA ASINGQMLIA GRLIQGIGAA
     LFMPSSLSLL AASYLDERAR ARMFGLWAAL VSAASALGPF IGGVLVQLAG WQSIFLINVP
     IGAAALISAY RILSRVPGKS SRVNIIGHLL GMMALGFLSY ALIQGPSAGW RSPVILVAFT
     AAVLAFVLFL LREISAKTPI LPASLYKNGR FSAAQFIGFL LNFALFGGMF MLSLFLQEAG
     GASSFMAGVE LLPMMAVFVI GNLLFARLAN RFEAGQLMFV SMAVSCIIAL LLFVLISPDF
     PYWQLAVLMS VMNLCTGITV PAMTTVIMQA AGQRHTNIAG AALNANRQIG ALVGVAITGV
     IIHLSATWYA GAGFAFLMMG AAYSLAALLV WLFLAAHNGT AASEKM
//

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