(data stored in ACNUC7421 zone)

HOGENOM: BORA1_1_PE1003

ID   BORA1_1_PE1003                       STANDARD;      PRT;   217 AA.
AC   BORA1_1_PE1003; Q2KV81;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Thiopurine S-methyltransferase; EC=2.1.1 67;AltName:
DE   Full=Thiopurine methyltransferase; (BORA1_1.PE1003).
GN   Name=tpm; OrderedLocusNames=BAV1018;
OS   BORDETELLA AVIUM 197N.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=360910;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BORA1_1.PE1003.
CC       Bordetella avium 197N, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:TPMT_BORA1
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + a thiopurine = S-
CC       adenosyl-L-homocysteine + a thiopurine S-methylether.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. TPMT
CC       family.
CC   -!- GENE_FAMILY: HOG000276919 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2KV81; -.
DR   EMBL; AM167904; CAJ48627.1; -; Genomic_DNA.
DR   RefSeq; YP_785541.1; NC_010645.1.
DR   STRING; Q2KV81; -.
DR   GeneID; 6266584; -.
DR   GenomeReviews; AM167904_GR; BAV1018.
DR   KEGG; bav:BAV1018; -.
DR   NMPDR; fig|521.1.peg.2766; -.
DR   OMA; QGDIFTL; -.
DR   ProtClustDB; PRK13255; -.
DR   BioCyc; ABAU360910:BAV1018-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008119; F:thiopurine S-methyltransferase activity; IEA:EC.
DR   HAMAP; MF_00812; Thiopur_methtran; 1; -.
DR   InterPro; IPR022474; Thiopur_S-MeTfrase_Se/Te_detox.
DR   InterPro; IPR008854; Thiopurine_S-MeTrfase.
DR   InterPro; IPR016822; Thiopurine_S-MeTrfase_sub.
DR   Pfam; PF05724; TPMT; 1.
DR   PIRSF; PIRSF023956; Thiopurine_S-methyltransferase; 1.
DR   TIGRFAMs; TIGR03840; TMPT_Se_Te; 1.
DR   HOGENOMDNA; BORA1_1.PE1003; -.
KW   Complete proteome; Cytoplasm; Methyltransferase;
KW   S-adenosyl-L-methionine; Transferase.
SQ   SEQUENCE   217 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDADFWLDRW REGKTGFHQD RVTPLLPKYW PRLALPTGAR VLVPLAGKSL DMVWLAEQGH
     EVLGVELSSL AVQQFFAEQG WAPRRWESAY GQHYAANGVE LICGDIFKLD DAALKDCLGV
     YDRAALVALP ETMRRAYANH VYGQMPAGYR GLLLTLDYPQ TQMEGPPFSV DEAEVQALFG
     EQAHLWDRRD ILEKEPKFAE RGVSRLDTLV FRLSAAS
//

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