(data stored in SCRATCH3701 zone)

HOGENOM6: BORBZ_4_PE412

ID   BORBZ_4_PE412                        STANDARD;      PRT;   810 AA.
AC   BORBZ_4_PE412; B7J201;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (BORBZ_4.PE412).
GN   Name=gyrA; OrderedLocusNames=BbuZS7_0441;
OS   BORRELIA BURGDORFERI ZS7.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Borrelia;
OC   Borrelia burgdorferi group.
OX   NCBI_TaxID=445985;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BORBZ_4.PE412.
CC       Borrelia burgdorferi ZS7, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:B7J201_BORBZ
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B7J201; -.
DR   EMBL; CP001205; ACK75164.1; -; Genomic_DNA.
DR   RefSeq; YP_002374946.1; NC_011728.1.
DR   ProteinModelPortal; B7J201; -.
DR   SMR; B7J201; 506-809.
DR   STRING; B7J201; -.
DR   EnsemblBacteria; EBBORT00000002982; EBBORP00000002721; EBBORG00000002982.
DR   GeneID; 7106244; -.
DR   GenomeReviews; CP001205_GR; BbuZS7_0441.
DR   KEGG; bbz:BbuZS7_0441; -.
DR   GeneTree; EBGT00050000007271; -.
DR   OMA; QRENVIV; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BORBZ_4.PE412; -.
DR   PRODOM; BORBZ_4_PE412.
DR   SWISS-2DPAGE; BORBZ_4_PE412.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   810 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAVGENKEQI LNVRIEDEIK TSYLNYAMSV IVSRALPDVR DGLKPVHRRI LYSMYEMGLR
     SDKAFKKAGR IVGDVLGKYH PHGDQSIYDA LVRLAQDFSL RYPVIRGQGN FGSIDGDPPA
     AMRYTEAKME KITEYIVKDI DKETVNFKSN YDDSLSEPEI MPSSFPFLLV NGSSGIAVGM
     ATNMAPHNLR EICDAIVYML DNENASIFDL LKIVKGPDFP TFGEIVYNDN LIKAYKTGKG
     SVVIRARYHI EERAEDRNAI IVTEIPYTVN KSALLMKVAL LAKEEKLEGL LDIRDESDRE
     GIRIVLEVKR GFDPHVIMNL LYEYTEFKKH FSINNLALVN GIPKQLNLEE LLFEFIEHRK
     NIIERRIEFD LRKAKEKAHV LEGLNIALNN IDEVIKIIKS SKLAKDARER LVSNFGLSEI
     QANSVLDMRL QKLTALEIFK LEEELNILLS LIKDYEDILL NPVRIINIIR EETINLGLKF
     GDERRTKIIY DEEVLKTSMS DLMQKENIVV MLTKKGFLKR LSQNEYKLQG TGGKGLSSFD
     LNDGDEIVIA LCVNTHDYLF MISNEGKLYL INAYEIKDSS RASKGQNISE LINLGDQEEI
     LTIKNSKDLT DDAYLLLTTA SGKIARFEST DFKAVKSRGV IVIKLNDKDF VTSAEIVFKD
     EKVICLSKKG SAFIFNSRDV RLTNRGTQGV CGMKLKEGDL FVKVLSVKEN PYLLIVSENG
     YGKRLNMSKI SELKRGATGY TSYKKSDKKA GSVVDAIAVS EDDEILLVSK RSKALRTVAG
     KVSEQGKDAR GIQVLFLDND SLVSVSKFIK
//

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