(data stored in SCRATCH3701 zone)

HOGENOM6: BORHD_1_PE417

ID   BORHD_1_PE417                        STANDARD;      PRT;   810 AA.
AC   BORHD_1_PE417; B2S0D7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (BORHD_1.PE417).
GN   Name=gyrA; OrderedLocusNames=BH0435;
OS   BORRELIA HERMSII DAH.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Borrelia.
OX   NCBI_TaxID=314723;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BORHD_1.PE417.
CC       Borrelia hermsii DAH chromosome, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:GYRA_BORHD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B2S0D7; -.
DR   EMBL; CP000048; AAX16943.1; -; Genomic_DNA.
DR   RefSeq; YP_001883863.1; NC_010673.1.
DR   STRING; B2S0D7; -.
DR   EnsemblBacteria; EBBORT00000006979; EBBORP00000006403; EBBORG00000006979.
DR   GeneID; 6277146; -.
DR   GenomeReviews; CP000048_GR; BH0435.
DR   KEGG; bhr:BH0435; -.
DR   GeneTree; EBGT00050000007271; -.
DR   OMA; QRENVIV; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; BHER314723:BH0435-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BORHD_1.PE417; -.
DR   PRODOM; BORHD_1_PE417.
DR   SWISS-2DPAGE; BORHD_1_PE417.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   810 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVTEEDKEQI LNIKIEDEVK TSYLNYAMSV IVSRALPDVR DGLKPVHRRI LYSMHEMGLR
     ADKAFKKAGR IVGDVLGKYH PHGDQSIYEA LVRLAQDFSL RYPIVIGQGN FGSIDGDPPA
     AMRYTEARMA RVAEELVRDI DKQTVDFRAN YDDSLLEPEV LPAAFPFLLV NGSSGIAVGM
     ATNMAPHNLK EICDAIVYML DHDSVSVYDL IEIVKGPDFP TYAEIIYNES LIKAYTTGKG
     SVVIRARYHI EEKFEDHIAI IITQIPYAVN KSSLLMKIAF LIKEEKLEGV SDIRDESDRE
     GIRIVLEIKK GFDPHVVMNL LYEYTELRKN FSINNLALVN GIPKQLNLKE LISAFIEHRK
     EIVRRRVEFD LKRAREKAHI LEGLNIALRN IDRVIEIIRF ARLVKDAKEC IIKEFNLSEI
     QANSILDMKL QKLTSIETEK LEEEFKILLA LIKDYEDILN SPERVVNIVR EEIINLSLKF
     GDERRTKIIY DEEVLKTSMS DLMQRENVIV ILTKQGFIKR ILQDEYKLQG IGGKGLGSFD
     LQDRDQVNIT LCVNTHDFLF MISNEGKLYV INAYGIKDTS RTSKGQNVRE LINLGETEEI
     LAIKNCNELS VDNYLLITTA NGKIARIETE GFKTVKARGV IVIKLDDNDF VTSAEIVSKN
     EKIICISKKG NAFAFNSDNI RLTHRGTQGV SGMKVREGDV LIKALAVKQG SHLLVVSENG
     YGKRLEISKV TDLKRGATGY TCYKKSDEKA GEVVDAITVV QDDEILLVSK GAKVLRTLVD
     KISEQGKDAR GMQVLSLDED KLISVSKFIK
//

If you have problems or comments...

PBIL Back to PBIL home page