(data stored in ACNUC8465 zone)

HOGENOM: BOVIN10_38_PE19

ID   BOVIN10_38_PE19                      STANDARD;      PRT;   234 AA.
AC   BOVIN10_38_PE19; Q17QI8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Rho-related GTP-binding protein RhoV; (BOVIN10_38.PE19).
GN   Name=Rhov;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN10_38.PE19.
CC       Bos taurus chromosome 10 Btau_4.0 partial sequence 35850657..36848620
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RHOV_BOVIN
CC   -!- FUNCTION: Plays a role in the control of the actin cytoskeleton
CC       via activation of the JNK pathway (By similarity).
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- SUBUNIT: Interacts with PAK2 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic
CC       side (By similarity). Endosome membrane; Lipid-anchor; Cytoplasmic
CC       side (By similarity). Note=Treatment with TNF activates endosomal
CC       but not plasma membrane RHOV (By similarity).
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rho family.
CC   -!- GENE_FAMILY: HOG000233974 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000016291;ENSBTAT00000021672;ENSBTAP00000021672.
DR   EMBL; BC118335; - ;
DR   UniProtKB/Swiss-Prot; Q17QI8; -.
DR   EMBL; BC118335; AAI18336.1; -; mRNA.
DR   IPI; IPI00686224; -.
DR   RefSeq; NP_001069567.1; NM_001076099.1.
DR   UniGene; Bt.61724; -.
DR   ProteinModelPortal; Q17QI8; -.
DR   SMR; Q17QI8; 31-208.
DR   STRING; Q17QI8; -.
DR   GeneID; 538143; -.
DR   KEGG; bta:538143; -.
DR   CTD; 171177; -.
DR   eggNOG; maNOG09005; -.
DR   GeneTree; ENSGT00560000076971; -.
DR   InParanoid; Q17QI8; -.
DR   OrthoDB; EOG4255TJ; -.
DR   PhylomeDB; Q17QI8; -.
DR   GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR003578; Small_GTPase_Rho.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00174; RHO; 1.
DR   TIGRFAMs; TIGR00231; Small_GTP; 1.
DR   PROSITE; PS51420; RHO; 1.
DR   HOGENOMDNA; BOVIN10_38.PE19; -.
KW   ENSBTAG00000016291fold_1320000031; ENSBTAP00000021672fold_1320000031;
KW   BC118335;
KW   Cell membrane; Complete proteome; Endosome; GTP-binding; Lipoprotein;
KW   Magnesium; Membrane; Metal-binding; Nucleotide-binding; Palmitate;
KW   Reference proteome.
SQ   SEQUENCE   234 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPPRELSEAE SSPLRSPTPP PGRGSASPEL GIKCVLVGDG AVGKSSLIVS YTCNGYPARY
     RPTALDTFSV QVLVDGAPVR IELWDTAGQE DLDRLRSLCY PDTDVFLACF SVVQPSSFQN
     ITEKWLPEIR THNPQAPVLL VGTQADLRDD VNVLIQLDQG GREGPVPQPQ AQGLAEKIRA
     CCYLECSALT HNNLKNVFDS SFSAIEHKPV ENKLNAKGVR TLSRCRWKKF FCFV
//

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