(data stored in ACNUC6288 zone)

HOGENOM: BOVIN11_77_PE14

ID   BOVIN11_77_PE14                      STANDARD;      PRT;   524 AA.
AC   BOVIN11_77_PE14; Q3T058;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Translation initiation factor eIF-2B subunit delta;AltName:
DE   Full=eIF-2B GDP-GTP exchange factor subunit delta; (BOVIN11_77.PE14).
GN   Name=EIF2B4;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN11_77.PE14.
CC       Bos taurus chromosome 11 Btau_4.0 partial sequence 74094966..75022373
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:EI2BD_BOVIN
CC   -!- FUNCTION: Catalyzes the exchange of eukaryotic initiation factor
CC       2-bound GDP for GTP (By similarity).
CC   -!- SUBUNIT: Complex of five different subunits; alpha, beta, gamma,
CC       delta and epsilon (By similarity).
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family.
CC   -!- GENE_FAMILY: HOG000176924 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000019510;ENSBTAT00000025991;ENSBTAP00000025991.
DR   EMBL; BC102555; - ;
DR   UniProtKB/Swiss-Prot; Q3T058; -.
DR   EMBL; BC102555; AAI02556.1; -; mRNA.
DR   IPI; IPI00707472; -.
DR   RefSeq; NP_001029716.1; NM_001034544.1.
DR   UniGene; Bt.48888; -.
DR   ProteinModelPortal; Q3T058; -.
DR   STRING; Q3T058; -.
DR   PRIDE; Q3T058; -.
DR   GeneID; 521926; -.
DR   KEGG; bta:521926; -.
DR   CTD; 8890; -.
DR   eggNOG; maNOG12585; -.
DR   GeneTree; ENSGT00550000075009; -.
DR   InParanoid; Q3T058; -.
DR   OrthoDB; EOG4MPHQ3; -.
DR   PhylomeDB; Q3T058; -.
DR   GO; GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.
DR   GO; GO:0003743; F:translation initiation factor activity; ISS:RefGenome.
DR   GO; GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.
DR   GO; GO:0042552; P:myelination; ISS:UniProtKB.
DR   GO; GO:0045947; P:negative regulation of translational initiation; ISS:RefGenome.
DR   GO; GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
DR   InterPro; IPR000649; IF-2B-related.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   HOGENOMDNA; BOVIN11_77.PE14; -.
KW   ENSBTAG00000019510fold_1320000031; ENSBTAP00000025991fold_1320000031;
KW   BC102555;
KW   Complete proteome; Initiation factor; Phosphoprotein;
KW   Protein biosynthesis; Reference proteome.
SQ   SEQUENCE   524 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MATAAVAVRE DSGSGMKAEL APRPGAEGRE MTQEEKLQLR KEKKQQKKKR KEEKGTETET
     GSAVSAAQCQ VGPAKHLAGP DSQLGTAKEK VPAGRSKAEL RAERRAKQEA ERALKQARKG
     DQGGPPPQAC PSTAGETPSG VKRLPEHSQV DDPTLLRRLV KKPERQQVPT RKDYGSKVSL
     FSHLPQYSRQ NSLTQFMSIP SSVIHPAMVR LGLQYSQGLV SGSNARCIAL LRALQQVIQD
     YTTPPSEELS RDLVNKLKPY FSFLTQCRPL SASMYNAIKF LNKEITGVSG SKREEEAKSE
     LRAAIDRYIK EKIVLAAQAI SRFAYKKISN GDVILVYGCS SLVSHILQEA WAKGRQFRVV
     VVDSRPRLEA KHTLRSLVRA GVPASYLLIP AASYVLPEVS KVLLGAHALL ANGSVMSRVG
     TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD PDDLLCERGE HVALANWQNH
     SSLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK SSDQ
//

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