(data stored in ACNUC9543 zone)

HOGENOM: BOVIN18_38_PE4

ID   BOVIN18_38_PE4                       STANDARD;      PRT;   1227 AA.
AC   BOVIN18_38_PE4; Q17R09;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16;
DE   EC=3.6.4 13;AltName: Full=ATP-dependent RNA helicase DHX38;AltName:
DE   Full=DEAH box protein 38; (BOVIN18_38.PE4).
GN   Name=DHX38; Synonyms=PRP16;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN18_38.PE4.
CC       Bos taurus chromosome 18 Btau_4.0 partial sequence 37140944..38140943
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:PRP16_BOVIN
CC   -!- FUNCTION: Probable ATP-binding RNA helicase involved in pre-mRNA
CC       splicing (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC   -!- SUBUNIT: Identified in the spliceosome C complex (By similarity).
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH
CC       subfamily. PRP16 sub-subfamily.
CC   -!- SIMILARITY: Contains 1 helicase ATP-binding domain.
CC   -!- SIMILARITY: Contains 1 helicase C-terminal domain.
CC   -!- GENE_FAMILY: HOG000175261 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000013265;ENSBTAT00000045480;ENSBTAP00000042866.
DR   EMBL; BC118085; - ;
DR   UniProtKB/Swiss-Prot; Q17R09; -.
DR   EMBL; BC118085; AAI18086.1; -; mRNA.
DR   IPI; IPI00690755; -.
DR   RefSeq; NP_001069266.1; NM_001075798.1.
DR   UniGene; Bt.42896; -.
DR   ProteinModelPortal; Q17R09; -.
DR   STRING; Q17R09; -.
DR   PRIDE; Q17R09; -.
DR   GeneID; 520046; -.
DR   KEGG; bta:520046; -.
DR   CTD; 9785; -.
DR   eggNOG; maNOG07381; -.
DR   GeneTree; ENSGT00590000083174; -.
DR   PhylomeDB; Q17R09; -.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR014001; DEAD-like_helicase.
DR   InterPro; IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR011709; DUF1605.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR001650; Helicase_C.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF04408; HA2; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   HOGENOMDNA; BOVIN18_38.PE4; -.
KW   ENSBTAG00000013265fold_1320000031; ENSBTAP00000042866fold_1320000031;
KW   BC118085;
KW   ATP-binding; Complete proteome; Helicase; Hydrolase; mRNA processing;
KW   mRNA splicing; Nucleotide-binding; Nucleus; Phosphoprotein;
KW   Reference proteome; Spliceosome.
SQ   SEQUENCE   1227 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEDSGEDASL HRLEGTDVDS QVGGLIFKTK SAASEQHVFK APAPRPSLLG LDLLASLKRK
     EREEKDDGED KKKSRISSYK DWEESKDDQR DAEAEDSDQA GRSGRKDRHY RSARVETPSH
     PGGVSEEFWE RSRQRERERR EHGVYASSKD EKDRKKERSR DRDCDRKRDR DERDRSRHSG
     RSERDGGSDR SSRRNEPESP RHRPKDAATP SRSTWEEEDS GYGSSRRSQW ESPSPTPSYR
     DSERSHRPSS RDRDRSVRSR YSDDTPLPTP SYKYNEWADD RRHLGSTPRL SRGRGRREDG
     EEGISFDTEE ERQQWEDDQR QADRDWYMMD EGYDEFHNPL AYSSDDYVRR REQHLHKQKQ
     KRISAQRRQI NEDNERWETN RMLTSGVVHR LEVDEDFEED SAAKVHLMVH NLVPPFLDGR
     IVFTKQPEPV IPVKDATSDL AIIARKGSQT VRKHREQKER KKAQHKHWEL AGTKLGDIMG
     VKKEEEPDKS LTEDGKVDYR TEQKFADHMK KKSEASSEFA KKKSILEQRQ YLPIFAVQQE
     LLTIIRDNSI VIVVGETGSG KTTQLTQYLH EDGYTDYGMI GCTQPRRVAA MSVAKRVSEE
     MGGNLGEEVG YAIRFEDCTS ESTLIKYMTD GILLRESLRE ADLDHYSAII MDEAHERSLN
     TDVLFGLLRE VVARRSDLKL IVTSATMDAE KFASFFGNVP IFHIPGRTFP VDILFSKTPQ
     EDYVEAAVKQ SLQVHLSGAP GDILIFMPGQ EDIEVTSDQI VEHLEELENA PALAVLPIYS
     QLPSDLQAKI FQKAPDGVRK CIVATNIAET SLTVDGIMFV IDSGYCKLKV SSPSLGVKVA
     ELXPISQANA NQRSGIAGRT GPGQCFRLYT QSAYKNELLT TTVPEIQRTN LANVVLLLKS
     LGVQDLLQFH FMDPPPEDNM LNSMYQLWIL GALDNTGGLT STGRLMVEFP LDPALSKMLI
     VSCDMGCSSE ILLIVSMLSV PAIFYRPKGR EEESDQIREK FAVPESDHLS YLNVYLQWKN
     NNYSTIWCND HFIHAKAMRK VREVRAQLKD IMVQQRMSLA SCGTDWDIVR KCICAAYFHQ
     AAKLKGIGEY VNIRTGMPCH LHPTSSLFGM GYTPDYIVYH ELVMTTKEYM QCVTAVDGEW
     LAELGPMFYS VKQAGKSRQE NRRRAKEEAS AMEEEMALAE EQLRARRQEQ EKRSPLGSVR
     STKIYTPGRK EQGEPMTPRR TPARFGL
//

If you have problems or comments...

PBIL Back to PBIL home page