(data stored in ACNUC22857 zone)

HOGENOM: BOVIN19_15_PE13

ID   BOVIN19_15_PE13                      STANDARD;      PRT;   951 AA.
AC   BOVIN19_15_PE13; Q08DS7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=AP-1 complex subunit beta-1;AltName: Full=Adapter-related
DE   protein complex 1 subunit beta-1;AltName: Full=Adaptor protein complex
DE   AP-1 subunit beta-1;AltName: Full=Beta-1-adaptin;AltName:
DE   Full=Beta-adaptin 1;AltName: Full=Clathrin assembly protein complex 1
DE   beta large chain;AltName: Full=Golgi adaptor HA1/AP1 adaptin beta
DE   subunit; (BOVIN19_15.PE13).
GN   Name=AP2B1;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN19_15.PE13.
CC       Bos taurus chromosome 19 Btau_4.0 partial sequence 13821062..14821061
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:AP1B1_BOVIN
CC   -!- FUNCTION: Subunit of clathrin-associated adaptor protein complex 1
CC       that plays a role in protein sorting in the late-Golgi/trans-Golgi
CC       network (TGN) and/or endosomes. The AP complexes mediate both the
CC       recruitment of clathrin to membranes and the recognition of
CC       sorting signals within the cytosolic tails of transmembrane cargo
CC       molecules (By similarity).
CC   -!- SUBUNIT: Adaptor protein complex 1 (AP-1) is an heterotetramer
CC       composed of two large adaptins (gamma-type subunit AP1G1 and beta-
CC       type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or
CC       AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or
CC       AP1S3) (By similarity).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasmic vesicle,
CC       clathrin-coated vesicle membrane; Peripheral membrane protein;
CC       Cytoplasmic side (By similarity). Golgi apparatus (By similarity).
CC       Note=Component of the coat surrounding the cytoplasmic face of
CC       coated vesicles located at the Golgi complex (By similarity).
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC   -!- GENE_FAMILY: HOG000163270 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000020316;ENSBTAT00000027076;ENSBTAP00000027076.
DR   EMBL; BC123583; - ;
DR   UniProtKB/Swiss-Prot; Q08DS7; -.
DR   EMBL; BC123583; AAI23584.1; -; mRNA.
DR   IPI; IPI00696360; -.
DR   RefSeq; NP_001068593.1; NM_001075125.1.
DR   UniGene; Bt.88309; -.
DR   ProteinModelPortal; Q08DS7; -.
DR   SMR; Q08DS7; 4-582, 716-951.
DR   STRING; Q08DS7; -.
DR   PRIDE; Q08DS7; -.
DR   Ensembl; ENSBTAT00000027076; ENSBTAP00000027076; ENSBTAG00000020316.
DR   GeneID; 282183; -.
DR   KEGG; bta:282183; -.
DR   CTD; 163; -.
DR   GeneTree; ENSGT00530000063138; -.
DR   InParanoid; Q08DS7; -.
DR   OMA; DCHLNAD; -.
DR   OrthoDB; EOG4PG607; -.
DR   PhylomeDB; Q08DS7; -.
DR   GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR   GO; GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   InterPro; IPR016342; AP_complex_bsu.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR012295; Beta2_adaptin/TATA-box-bd_C.
DR   InterPro; IPR009028; Calthrin/coatomer_app_sub_C.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   InterPro; IPR013041; Clathrin/coatomer_app_Ig-like.
DR   InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR   InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR   InterPro; IPR015151; Clathrin_b-adaptin_app_sub_C.
DR   Gene3D; G3DSA:1.25.10.10; ARM-like; 1.
DR   Gene3D; G3DSA:3.30.310.10; b_Adaptin_TBP_C; 1.
DR   Gene3D; G3DSA:2.60.40.1150; Clathrin_b-adaptin_app_Ig-like; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   Pfam; PF02883; Alpha_adaptinC2; 1.
DR   Pfam; PF09066; B2-adapt-app_C; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 1.
DR   SMART; SM00809; Alpha_adaptinC2; 1.
DR   SUPFAM; SSF55711; AP2_adap_app; 1.
DR   SUPFAM; SSF48371; ARM-type_fold; 1.
DR   SUPFAM; SSF49348; Clath_adapt; 1.
DR   HOGENOMDNA; BOVIN19_15.PE13; -.
KW   ENSBTAG00000020316fold_1320000031; ENSBTAP00000027076fold_1320000031;
KW   BC123583;
KW   Acetylation; Complete proteome; Cytoplasmic vesicle; Endocytosis;
KW   Golgi apparatus; Membrane; Phosphoprotein; Protein transport;
KW   Reference proteome; Transport.
SQ   SEQUENCE   951 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDSKYFTTN KKGEIFELKA ELNNEKKEKR KEAVKKVIAA MTVGKDVSSL FPDVVNCMQT
     DNLELKKLVY LYLMNYAKSQ PDMAIMAVNS FVKDCEDPNP LIRALAVRTM GCIRVDKITE
     YLCEPLRKCL KDEDPYVRKT AAVCVAKLHD INAQMVEDQG FLDSLRDLIA DSNPMVVANA
     VAALSEISES HPNSNLLDLN PQNINKLLTA LNECTEWGQI FILDCLSNYN PKDDREAQSI
     CERVTPRLSH ANSAVVLSAV KVLMKFLELL PKESDYYNML LKKLAPPLVT LLSGEPEVQY
     VALRNINLIV QKRPEILKQE IKVFFVKYND PIYVKLEKLD IMIRLASQAN IAQVLAELKE
     YATEVDVDFV RKAVRAIGRC AIKVEQSAER CVSTLLDLIQ TKVNYVVQEA IVVIRDIFRK
     YPNKYESIIA TLCENLDSLD EPDARAAMIW IVGEYAERID NADELLESFL EGFHDESTQV
     QLTLLTAIVK LFLKKPSETQ ELVQQVLSLA TQDSDNPDLR DRGYIYWRLL STDPVTAKEV
     VLSEKPLISE ETDLIEPTLL DELICHIGSL ASVYHKPPNA FVEGSHGIHR KHLPIHHGST
     DAGDSPVGTT TATNLEQPQV IPSQGDLLGD LLNLDLGPPV NVPQVSSMQM GAVDLLGGGL
     DSLLGSDLGG GIGGSPAVGQ SFIPSSVPAT FAPSPTPAVV SSGLNDLFEL STGIGMAPGG
     YVAPKAVWLP AVKAKGLEIS GTFTHRQGHI YMEMNFTNKA LQHMTDFAIQ FNKNSFGVIP
     STPLAIHTPL MPNQSIDVSL PLNTLGPVMK MEPLNNLQVA VKNNIDVFYF SCLIPLNVLF
     VEDGKMERQV FLATWKDIPN ENELQFQIKE CHLNADTVSS KLQNNNVYTI AKRNVEGQDM
     LYQSLKLTNG IWILAELRIQ PGNPNYTLSL KCRAPEVSQY IYQVYDSILK N
//

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