(data stored in ACNUC13676 zone)

HOGENOM: BOVIN25_40_PE11

ID   BOVIN25_40_PE11                      STANDARD;      PRT;   452 AA.
AC   BOVIN25_40_PE11; Q29RY8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=AP-4 complex subunit mu-1;AltName: Full=AP-4 adapter
DE   complex mu subunit;AltName: Full=Adapter-related protein complex 4 mu-1
DE   subunit;AltName: Full=Mu subunit of AP-4;AltName: Full=Mu-adaptin-related
DE   protein 2; Short=mu-ARP2;AltName: Full=Mu4-adaptin; Short=mu4;
DE   (BOVIN25_40.PE11).
GN   Name=AP4M1;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN25_40.PE11.
CC       Bos taurus chromosome 25 Btau_4.0 partial sequence 38333819..39333818
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:AP4M1_BOVIN
CC   -!- FUNCTION: Subunit of novel type of clathrin- or non-clathrin-
CC       associated protein coat involved in targeting proteins from the
CC       trans-Golgi network (TGN) to the endosomal-lysosomal system (By
CC       similarity).
CC   -!- SUBUNIT: Adapter-like complex 4 (AP-4) is an heterotetramer
CC       composed of two large adaptins (epsilon-type subunit AP4E1 and
CC       beta-type subunit AP4B1), a medium adaptin (mu-type subunit AP4M1)
CC       and a small adaptin (sigma-type AP4S1). Interacts with the C-
CC       terminal domain of GRID2 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network (By
CC       similarity). Membrane, coated pit (By similarity). Note=Associated
CC       with the trans-Golgi network. Found in soma and dendritic shafts
CC       of neuronal cells (By similarity).
CC   -!- DOMAIN: Interacts specifically with tyrosine-based sorting signals
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the adaptor complexes medium subunit
CC       family.
CC   -!- SIMILARITY: Contains 1 MHD (mu homology) domain.
CC   -!- GENE_FAMILY: HOG000173245 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000002881;ENSBTAT00000003736;ENSBTAP00000003736.
DR   EMBL; BC113334; - ;
DR   UniProtKB/Swiss-Prot; Q29RY8; -.
DR   EMBL; BC113334; AAI13335.1; -; mRNA.
DR   IPI; IPI00697299; -.
DR   RefSeq; NP_001070567.1; NM_001077099.1.
DR   UniGene; Bt.59228; -.
DR   ProteinModelPortal; Q29RY8; -.
DR   PRIDE; Q29RY8; -.
DR   Ensembl; ENSBTAT00000003736; ENSBTAP00000003736; ENSBTAG00000002881.
DR   GeneID; 768040; -.
DR   KEGG; bta:768040; -.
DR   CTD; 9179; -.
DR   eggNOG; maNOG13778; -.
DR   GeneTree; ENSGT00530000062779; -.
DR   InParanoid; Q29RY8; -.
DR   OMA; CGNANPH; -.
DR   OrthoDB; EOG4RJG1M; -.
DR   PhylomeDB; Q29RY8; -.
DR   GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR   GO; GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR022775; AP_mu_sigma_su.
DR   InterPro; IPR001392; Clathrin_mu.
DR   InterPro; IPR008968; Clathrin_mu_C.
DR   InterPro; IPR018240; Clathrin_mu_CS.
DR   InterPro; IPR011012; Longin-like.
DR   Pfam; PF00928; Adap_comp_sub; 1.
DR   Pfam; PF01217; Clat_adaptor_s; 1.
DR   PIRSF; PIRSF005992; Clathrin_mu; 1.
DR   PRINTS; PR00314; CLATHRINADPT.
DR   SUPFAM; SSF49447; AP50; 1.
DR   SUPFAM; SSF64356; Longin_like; 1.
DR   PROSITE; PS00990; CLAT_ADAPTOR_M_1; FALSE_NEG.
DR   PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR   PROSITE; PS51072; MHD; 1.
DR   HOGENOMDNA; BOVIN25_40.PE11; -.
KW   ENSBTAG00000002881fold_1320000031; ENSBTAP00000003736fold_1320000031;
KW   BC113334;
KW   Coated pit; Complete proteome; Golgi apparatus; Membrane;
KW   Phosphoprotein; Protein transport; Reference proteome; Transport.
SQ   SEQUENCE   452 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MISQFFILSS KGDPLIYKDF RGDSGGRDVA ELFYRKLTGL PGDESPVVMH HDDRHFIHIR
     HSGLYLVATT SENISPFSLL ELLSRLATLL GDYCGSLGEA TISRNVALVY ELLDEVLDYG
     YVQTTSTEVL RNFIQTEAVV SKPFSLFDLS SVGLFGAETQ QSKVAPSSAA SRPVLSSRSD
     QSQKNEVFLD VVERLSVLIA SNGSLLKVDV QGEIRLKSFL PSGSEMRIGL TEEFCVGKSE
     LRGYGPGIRV DEVSFHSSVY LDEFESHRIL RLQPPQGELT VMRYQLSDDL PSPLPFRLFP
     SVQWDRGSGR LQVYLKLRCD LPPKSQALNV RLHLPLPRGV VSLSQELSSP EQKAELGEGA
     LRWDLPRVQG GSQLSGLFQM DVPGLPGPPG QGPSASAPLG LGPASLSFEL PRHTCSGLQV
     RFLRLAFRPC GNANPHKWVR HLSHSDAYVI RI
//

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