(data stored in ACNUC10964 zone)

HOGENOM: BOVIN25_44_PE13

ID   BOVIN25_44_PE13                      STANDARD;      PRT;   459 AA.
AC   BOVIN25_44_PE13; Q2KHV6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Sorting nexin-8; (BOVIN25_44.PE13).
GN   Name=SNX8;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN25_44.PE13.
CC       Bos taurus chromosome 25 Btau_4.0 partial sequence 42242875..43242874
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:SNX8_BOVIN
CC   -!- FUNCTION: May be involved in several stages of intracellular
CC       trafficking. May play a role in intracellular protein transport
CC       from early endosomes to the trans-Golgi network (By similarity).
CC   -!- SUBCELLULAR LOCATION: Early endosome membrane; Peripheral membrane
CC       protein; Cytoplasmic side (By similarity). Note=Colocalizes with
CC       retromer components (By similarity).
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC   -!- SIMILARITY: Contains 1 PX (phox homology) domain.
CC   -!- GENE_FAMILY: HOG000252992 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000013708;ENSBTAT00000018213;ENSBTAP00000018213.
DR   EMBL; BC112867; - ;
DR   UniProtKB/Swiss-Prot; Q2KHV6; -.
DR   EMBL; BC112867; AAI12868.1; -; mRNA.
DR   IPI; IPI00711549; -.
DR   RefSeq; NP_001039998.1; NM_001046533.1.
DR   UniGene; Bt.28467; -.
DR   ProteinModelPortal; Q2KHV6; -.
DR   PRIDE; Q2KHV6; -.
DR   Ensembl; ENSBTAT00000018213; ENSBTAP00000018213; ENSBTAG00000013708.
DR   GeneID; 614344; -.
DR   KEGG; bta:614344; -.
DR   CTD; 29886; -.
DR   eggNOG; maNOG06194; -.
DR   GeneTree; ENSGT00460000041594; -.
DR   InParanoid; Q2KHV6; -.
DR   OMA; LYCLHQE; -.
DR   OrthoDB; EOG42JNRD; -.
DR   PhylomeDB; Q2KHV6; -.
DR   GO; GO:0031901; C:early endosome membrane; ISS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0034498; P:early endosome to Golgi transport; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   InterPro; IPR001683; Phox.
DR   Gene3D; G3DSA:3.30.1520.10; PX; 1.
DR   Pfam; PF00787; PX; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; PX; 1.
DR   PROSITE; PS50195; PX; 1.
DR   HOGENOMDNA; BOVIN25_44.PE13; -.
KW   ENSBTAG00000013708fold_1320000031; ENSBTAP00000018213fold_1320000031;
KW   BC112867;
KW   Complete proteome; Endosome; Lipid-binding; Membrane;
KW   Protein transport; Reference proteome; Transport.
SQ   SEQUENCE   459 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTGGAMDPLP TAPGAAAAEA EVDEEADPPA ADSPVPPVSE PRAPDAGQMQ VPPGNPLLLS
     LTLQELLARD AVQVELVPEK KGLFLKHVEY EVSSQRFKSC VYRRYNDFVV FHETLLHKFP
     YRMVPALPPK RMLGADREFI EARRRALKRF INLVARHPPF SEDTILKLFL SFSGPDVQNK
     LKESAQCLGD EFMNCRLAAR AKDFLPADIQ TQFAMSRELI RNIYNSFHKL RDRAERMVSR
     AIDNAADLLI FGKELSALGS DTTPLPSWAS LNSSTWGSLK QALKGLSVEF ALLADKAAQQ
     GKQEENDVVE KLNLFLDLLQ SYKDLCERHE KGVLHKHQRA LHKYSLMKRQ MVSAAVQSRE
     PESMEQLESR IVQQENVIQT MELRSHFSLY CLHQETQLVH VYLPLTSHIL GAFVNSQIQG
     HKEMSKVWND LQPKLRCLFV GPHGAPAPPR PPQDGLSAH
//

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