(data stored in ACNUC17492 zone)

HOGENOM: BOVIN3_8_PE1

ID   BOVIN3_8_PE1                         STANDARD;      PRT;   181 AA.
AC   BOVIN3_8_PE1; Q3T0T8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Regulator of G-protein signaling 5; Short=RGS5;
DE   (BOVIN3_8.PE1).
GN   Name=RGS5;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN3_8.PE1.
CC       Bos taurus chromosome 3 Btau_4.0 partial sequence 6916716..7702622
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RGS5_BOVIN
CC   -!- FUNCTION: Inhibits signal transduction by increasing the GTPase
CC       activity of G protein alpha subunits thereby driving them into
CC       their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha,
CC       but not to G(s)-alpha (By similarity).
CC   -!- SIMILARITY: Contains 1 RGS domain.
CC   -!- GENE_FAMILY: HOG000233512 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000016341;ENSBTAT00000032193;ENSBTAP00000032130.
DR   EMBL; BC102265; - ;
DR   UniProtKB/Swiss-Prot; Q3T0T8; -.
DR   EMBL; BC102265; AAI02266.1; -; mRNA.
DR   IPI; IPI00710032; -.
DR   RefSeq; NP_001029879.1; NM_001034707.1.
DR   UniGene; Bt.92767; -.
DR   ProteinModelPortal; Q3T0T8; -.
DR   SMR; Q3T0T8; 44-180.
DR   PRIDE; Q3T0T8; -.
DR   Ensembl; ENSBTAT00000032193; ENSBTAP00000032130; ENSBTAG00000016341.
DR   GeneID; 540509; -.
DR   KEGG; bta:540509; -.
DR   CTD; 8490; -.
DR   eggNOG; maNOG17871; -.
DR   GeneTree; ENSGT00600000084096; -.
DR   InParanoid; Q3T0T8; -.
DR   OMA; HSCLERA; -.
DR   OrthoDB; EOG41RPW5; -.
DR   PhylomeDB; Q3T0T8; -.
DR   GO; GO:0005737; C:cytoplasm; ISS:RefGenome.
DR   GO; GO:0005886; C:plasma membrane; ISS:RefGenome.
DR   GO; GO:0005096; F:GTPase activator activity; ISS:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000342; Regulat_G_prot_signal.
DR   InterPro; IPR024066; Regulat_G_prot_signal_dom1.
DR   InterPro; IPR016137; Regulat_G_prot_signal_superfam.
DR   Gene3D; G3DSA:1.10.196.10; G3DSA:1.10.196.10; 1.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulat_G_prot_signal_superfam; 1.
DR   PROSITE; PS50132; RGS; 1.
DR   HOGENOMDNA; BOVIN3_8.PE1; -.
KW   ENSBTAG00000016341fold_1320000031; ENSBTAP00000032130fold_1320000031;
KW   BC102265;
KW   Complete proteome; Reference proteome; Signal transduction inhibitor.
SQ   SEQUENCE   181 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCKGLAALPH SCLERAKEIK IKLGILLQKP ESAIDLVIPY NEKPEKPAKT QKPSLDEALQ
     WRDSLDKLLQ NNYGLASFKS FLKSEFSEEN LEFWMACEDY KKIKSPVKMA ETAKKIYEEF
     IQVEAPKEVN IDHFTKEITV KNLVEPSPSS FDVAQKRIHA LMEKDSLPRF VRSEFYQEFI
     K
//

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