(data stored in ACNUC10243 zone)

HOGENOM: BOVIN4_76_PE3

ID   BOVIN4_76_PE3                        STANDARD;      PRT;   341 AA.
AC   BOVIN4_76_PE3; Q2HJ60;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Heterogeneous nuclear ribonucleoproteins A2/B1; Short=hnRNP
DE   A2/B1; (BOVIN4_76.PE3).
GN   Name=HNRNPA2B1; Synonyms=HNRPA2B1;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN4_76.PE3.
CC       Bos taurus chromosome 4 Btau_4.0 partial sequence 71723244..72723243
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:ROA2_BOVIN
CC   -!- FUNCTION: Involved with pre-mRNA processing. Forms complexes
CC       (ribonucleosomes) with at least 20 other different hnRNP and
CC       heterogeneous nuclear RNA in the nucleous (By similarity).
CC   -!- SUBUNIT: Identified in the spliceosome C complex. Identified in a
CC       mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG,
CC       HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU,
CC       HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4,
CC       PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2,
CC       YBX1 and untranslated mRNAs. Interacts with IGF2BP1 (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm (By similarity).
CC       Cytoplasm (By similarity). Note=Localized in cytoplasmic mRNP
CC       granules containing untranslated mRNAs. Component of
CC       ribonucleosomes. Predominantly nucleoplasmic, but also found in
CC       the cytoplasm of cells in some tissues. Not found in the nucleolus
CC       (By similarity).
CC   -!- SIMILARITY: Contains 2 RRM (RNA recognition motif) domains.
CC   -!- GENE_FAMILY: HOG000234442 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000005726;ENSBTAT00000007527;ENSBTAP00000007527.
DR   EMBL; BC113298; - ;
DR   UniProtKB/Swiss-Prot; Q2HJ60; -.
DR   EMBL; BC113298; AAI13299.1; -; mRNA.
DR   IPI; IPI00695201; -.
DR   RefSeq; NP_001039440.1; NM_001045975.1.
DR   UniGene; Bt.48137; -.
DR   ProteinModelPortal; Q2HJ60; -.
DR   SMR; Q2HJ60; 3-181.
DR   STRING; Q2HJ60; -.
DR   PRIDE; Q2HJ60; -.
DR   Ensembl; ENSBTAT00000007527; ENSBTAP00000007527; ENSBTAG00000005726.
DR   GeneID; 507564; -.
DR   KEGG; bta:507564; -.
DR   CTD; 3181; -.
DR   eggNOG; maNOG08914; -.
DR   GeneTree; ENSGT00540000069937; -.
DR   OrthoDB; EOG4HQDKF; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait.
DR   InterPro; IPR000504; RRM_dom.
DR   Gene3D; G3DSA:3.30.70.330; a_b_plait_nuc_bd; 1.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   PROSITE; PS50102; RRM; 2.
DR   HOGENOMDNA; BOVIN4_76.PE3; -.
KW   ENSBTAG00000005726fold_1320000031; ENSBTAP00000007527fold_1320000031;
KW   BC113298;
KW   Acetylation; Complete proteome; Cytoplasm; Methylation;
KW   mRNA processing; mRNA splicing; Nucleus; Phosphoprotein;
KW   Reference proteome; Repeat; Ribonucleoprotein; RNA-binding;
KW   Spliceosome.
SQ   SEQUENCE   341 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEREKEQFRK LFIGGLSFET TEESLRNYYE QWGKLTDCVV MRDPASKRSR GFGFVTFSSM
     AEVDAAMAAR PHSIDGRVVE PKRAVAREES GKPGAHVTVK KLFVGGIKED TEEHHLRDYF
     EEYGKIDTIE IITDRQSGKK RGFGFVTFDD HDPVDKIVLQ KYHTINGHNA EVRKALSRQE
     MQEVQSSRSG RGGNFGFGDS RGGGGNFGPG PGSNFRGGSD GYGSGRGFGD GYNGYGGGPG
     GGNFGGSPGY GGGRGGYGGG GPGYGNQGGG YGGGYDNYGG GNYGSGNYND FGNYNQQPSN
     YGPMKSGNFG GSRNMGGPYG GGNYGPGGSG GSGGYGGRSR Y
//

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