(data stored in ACNUC7421 zone)

HOGENOM: BOVIN7_11_PE20

ID   BOVIN7_11_PE20                       STANDARD;      PRT;   365 AA.
AC   BOVIN7_11_PE20; Q2NL31;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   Flags: Fragments;
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase;AltName:
DE   Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like
DE   protein; (BOVIN7_11.PE20).
GN   Name=MRI1;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVIN7_11.PE20.
CC       Bos taurus chromosome 7 Btau_4.0 partial sequence 9682327..10406725
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:MTNA_BOVIN
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000002524;ENSBTAT00000003273;ENSBTAP00000003273.
DR   EMBL; BC111154; - ;
DR   UniProtKB/Swiss-Prot; Q2NL31; -.
DR   EMBL; BC111154; AAI11155.1; -; mRNA.
DR   IPI; IPI00714598; -.
DR   RefSeq; NP_001039852.1; NM_001046387.1.
DR   UniGene; Bt.10874; -.
DR   ProteinModelPortal; Q2NL31; -.
DR   STRING; Q2NL31; -.
DR   GeneID; 534734; -.
DR   KEGG; bta:534734; -.
DR   CTD; 84245; -.
DR   eggNOG; maNOG10591; -.
DR   GeneTree; ENSGT00390000013732; -.
DR   InParanoid; Q2NL31; -.
DR   OrthoDB; EOG41C6WN; -.
DR   PhylomeDB; Q2NL31; -.
DR   GO; GO:0005737; C:cytoplasm; ISS:RefGenome.
DR   GO; GO:0005634; C:nucleus; ISS:RefGenome.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; ISS:RefGenome.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; ISS:RefGenome.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; BOVIN7_11.PE20; -.
KW   ENSBTAG00000002524fold_1320000031; ENSBTAP00000003273fold_1320000031;
KW   BC111154;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Methionine biosynthesis; Nucleus; Reference proteome.
SQ   SEQUENCE   365 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     VSATVDSMTL EAIRYSRGSL QILDQLLLPQ QSRYEAVGSV RQAWEAIRAM KVRGAPAIAL
     VGCLSLAVEL QAGAGGPGLA ALVAFVQDAL SFLVTARPTA VNMARAARDL ADLAAQEAER
     EGATEEAVRE RVICWAEDML DKDLRDNRSI GDLGAHHLLK RAAPQGGKVT VLTHCNTGAL
     ATAGYGTALG VIRSLHNLGR LEHAFCTETR PYNQGARLTA FELVYEQIPA TLIADSMAAA
     AMAHQGVSAV VVGADRVVAN GDTANKVGTY QLAIAAKHHG IPFYVAAPSS SCDLRLETGR
     EIVIEERPDQ ELTDVNGVRI AAPGIGVWNP AFDVTPHDLI TGGIITELGV FAPEELQAAL
     SATIS
//

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