(data stored in ACNUC7421 zone)

HOGENOM: BOVINX_8_PE9

ID   BOVINX_8_PE9                         STANDARD;      PRT;   183 AA.
AC   BOVINX_8_PE9; Q08DI5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ras-related protein Rap-2c;Flags: Precursor;
DE   (BOVINX_8.PE9).
GN   Name=RAP2C;
OS   BOS TAURUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BOVINX_8.PE9.
CC       Bos taurus chromosome X Btau_4.0 partial sequence 6998759..7998758
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RAP2C_BOVIN
CC   -!- FUNCTION: Small GTP-binding protein which cycles between a GDP-
CC       bound inactive and a GTP-bound active form. May play a role in
CC       cytoskeletal rearrangements and regulate cell spreading through
CC       activation of the effector TNIK. May play a role in SRE-mediated
CC       gene transcription (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Recycling
CC       endosome membrane; Lipid-anchor; Cytoplasmic side (By similarity).
CC   -!- PTM: Palmitoylated. Palmitoylation is required for association
CC       with recycling endosome membranes and activation of TNIK (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Ras family.
CC   -!- GENE_FAMILY: HOG000233973 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Bos_taurus;ENSBTAG00000004131;ENSBTAT00000005408;ENSBTAP00000005408.
DR   EMBL; BC123730; - ;
DR   UniProtKB/Swiss-Prot; Q08DI5; -.
DR   EMBL; BC123730; AAI23731.1; -; mRNA.
DR   IPI; IPI00717286; -.
DR   RefSeq; NP_001069168.1; NM_001075700.1.
DR   UniGene; Bt.26628; -.
DR   ProteinModelPortal; Q08DI5; -.
DR   SMR; Q08DI5; 1-167.
DR   PRIDE; Q08DI5; -.
DR   Ensembl; ENSBTAT00000005408; ENSBTAP00000005408; ENSBTAG00000004131.
DR   GeneID; 515181; -.
DR   KEGG; bta:515181; -.
DR   CTD; 57826; -.
DR   eggNOG; maNOG10233; -.
DR   GeneTree; ENSGT00560000076632; -.
DR   InParanoid; Q08DI5; -.
DR   OMA; CCTTCIV; -.
DR   OrthoDB; EOG4P2Q3G; -.
DR   PhylomeDB; Q08DI5; -.
DR   GO; GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR020849; Small_GTPase_Ras.
DR   PANTHER; PTHR24070; PTHR24070; 1.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00173; RAS; 1.
DR   TIGRFAMs; TIGR00231; Small_GTP; 1.
DR   PROSITE; PS51421; RAS; 1.
DR   HOGENOMDNA; BOVINX_8.PE9; -.
KW   ENSBTAG00000004131fold_1320000031; ENSBTAP00000005408fold_1320000031;
KW   BC123730;
KW   Complete proteome; Cytoplasm; Endosome; GTP-binding; Lipoprotein;
KW   Membrane; Methylation; Nucleotide-binding; Palmitate; Phosphoprotein;
KW   Prenylation; Reference proteome.
SQ   SEQUENCE   183 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MREYKVVVLG SGGVGKSALT VQFVTGTFIE KYDPTIEDFY RKEIEVDSSP SVLEILDTAG
     TEQFASMRDL YIKNGQGFIL VYSLVNQQSF QDIKPMRDQI VRVKRYEKVP LILVGNKVDL
     EPEREVMSSE GRALAQEWGC PFMETSAKSK SMVDELFAEI VRQMNYSSLP EKQDQCCTTC
     VVQ
//

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