(data stored in SCRATCH3701 zone)

HOGENOM6: BRUMC_2_PE1059

ID   BRUMC_2_PE1059                       STANDARD;      PRT;   922 AA.
AC   BRUMC_2_PE1059; C7LC50;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (BRUMC_2.PE1059).
GN   Name=gyrA; OrderedLocusNames=BMI_I1109;
OS   BRUCELLA MICROTI CCM 4915.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae;
OC   Brucella.
OX   NCBI_TaxID=568815;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BRUMC_2.PE1059.
CC       Brucella microti CCM 4915 chromosome 1, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C7LC50_BRUMC
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C7LC50; -.
DR   EMBL; CP001578; ACU48085.1; -; Genomic_DNA.
DR   RefSeq; YP_003107034.1; NC_013119.1.
DR   STRING; C7LC50; -.
DR   GeneID; 8320670; -.
DR   GenomeReviews; CP001578_GR; BMI_I1109.
DR   KEGG; bmr:BMI_I1109; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BRUMC_2.PE1059; -.
DR   PRODOM; BRUMC_2_PE1059.
DR   SWISS-2DPAGE; BRUMC_2_PE1059.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   922 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNGGPNGGPS GIEPISIIEE MQRSYLDYAM SVIVSRALPD VRDGLKPVHR RILHAMNEMN
     LAYNRPYRKS AGVVGEVMGK YHPHGDASIY DALVRMAQDF SMRDPLIDGQ GNFGSIDGDP
     PAAMRYTECR LEKVTKSLLS DIDKDTVNFQ DNYDGREQEP VVLPARFPNL LVNGSGGIAV
     GMATNIPPHN LGEVIDGCVA LIDNPAIELS ELMELIPGPD FPTGGIILGR NGINSAYTTG
     RGSVIMRGRA TIEPMRGDRE AIIITEIPYQ VNKASMIEKM AELVRDKRID GISDLRDESD
     REGYRVVVEL KRDAVADVVL NQLYRYTPLQ TSFGCNMVAL NGGKPEQLTL LDMLRAFVAF
     REEVVTRRTK FLLNKARDRA HVLVGLAIAV ANIDEVIALI RRAPDPATAR EQLMERRWPA
     VDVAPLIRLI DDPRHTLNED NTYNLSEEQA RAILDLRLQR LTALGRDEVA DELNKIGEEI
     RDYLDILGSR LRVMNIVKEE MIAVRDEFAT PRRTEIGFGG AEMDDEDLIA REDMVVTVSH
     AGYIKRVPLT TYRAQRRGGK GRSGMATKEE DFVTRLFVAN THTPVLFFSS RGIVYKEKVW
     RLPVGTPQSR GKALINMLPL QQGERITTIM PLPEDEDSWA NLDVMFSTTR GTVRRNKLSD
     FVQVNRNGKI AMKLEDEGDE ILSVDTCTEF DDVLLTCAGG QCIRFPVTDV RVFAGRNSIG
     VRGINLAEGD KVISMAILHH VDATPAERSA YLKRSIAERR AQGADDADDI VVVGEDVDAE
     AELSEDRYQE LKAREETVLT VSEFGYGKRS SSYEFRISGR GGKGIRATDT SKTDEIGKLV
     ALFPVEGSDQ ILLVSDGGQL IRVPVDGIRI AGRSTKGVTI FNTADGEKVV SVERISDADS
     DEENGNGGDA APEGDTPAGT QE
//

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