(data stored in ACNUC7421 zone)

HOGENOM: BUMAL1_1_PE100

ID   BUMAL1_1_PE100                       STANDARD;      PRT;   533 AA.
AC   BUMAL1_1_PE100; Q62MV6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Glutamate--cysteine ligase; EC=6.3.2 2;AltName:
DE   Full=Gamma-ECS;AltName: Full=Gamma-glutamylcysteine synthetase;
DE   (BUMAL1_1.PE100).
GN   Name=gshA; OrderedLocusNames=BMA0117;
OS   BURKHOLDERIA MALLEI ATCC 23344.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=243160;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BUMAL1_1.PE100.
CC       Burkholderia mallei ATCC 23344 chromosome 1, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q62MV6_BURMA
CC   -!- CATALYTIC ACTIVITY: ATP + L-glutamate + L-cysteine = ADP +
CC       phosphate + gamma-L-glutamyl-L-cysteine.
CC   -!- PATHWAY: Sulfur metabolism; glutathione biosynthesis; glutathione
CC       from L-cysteine and L-glutamate: step 1/2.
CC   -!- SIMILARITY: Belongs to the glutamate--cysteine ligase type 1
CC       family.
CC   -!- SIMILARITY: Belongs to the glutamate--cysteine ligase type 1
CC       family. Type 1 subfamily.
CC   -!- GENE_FAMILY: HOG000266224 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q62MV6; -.
DR   EMBL; CP000010; AAU48669.1; -; Genomic_DNA.
DR   RefSeq; YP_101961.1; NC_006348.1.
DR   ProteinModelPortal; Q62MV6; -.
DR   GeneID; 3090433; -.
DR   GenomeReviews; CP000010_GR; BMA0117.
DR   KEGG; bma:BMA0117; -.
DR   TIGR; BMA0117; -.
DR   OMA; ADTLYLP; -.
DR   PhylomeDB; Q62MV6; -.
DR   ProtClustDB; PRK02107; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004357; F:glutamate-cysteine ligase activity; IEA:HAMAP.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00578; Glu_cys_ligase; 1; -.
DR   InterPro; IPR007370; Glu_cys_ligase.
DR   InterPro; IPR006334; Glut_cys_ligase.
DR   Pfam; PF04262; Glu_cys_ligase; 1.
DR   TIGRFAMs; TIGR01434; Glu_cys_ligase; 1.
DR   HOGENOMDNA; BUMAL1_1.PE100; -.
KW   ATP-binding; Complete proteome; Glutathione biosynthesis; Ligase;
KW   Nucleotide-binding.
SQ   SEQUENCE   533 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTSRQTELLQ QRLAVLSTSP TREQLPDGLR GIEKESLRVT RDGMIAFTPH PRALGSALTH
     PSLTTDYSEA LVELITPAER DAATTLERLD ELHRYVYASL GDEMLWTDSM PGLLPADDEI
     PIADYGTSNI GRLKTVYRRG LAYRYGRTMQ CIAGIHYNYS LSEEVWRRLH AEEGSTASIV
     DYQSERYLAL IRNFRRTSWL LMYLFGASPA LDAGFLRGRA HKLDTFDAAT LYRPHATSLR
     MSDLGYSNTT AQAALQADYN TLSGYLDALS KAVSEPYPPY EAIGTHRDGE WIQINTNVLQ
     IENEFYSTIR PKRVTYSGER PLHALASRGV QYIEVRCLDI DPFEPTGIAL DTARFLDAYL
     LVCALDESAP LTCDAYRESN ANFGRVTMEG RKPGLELTRD GAAVPMRAWA DEIFAQIEAA
     GRVLDDIRGD DTHARAIAAQ RAKLDDPELT SSARVLRAMR ENGQSFLEFA RAQSAAHAAY
     FHGRPLDEAA TRDARALAER SLAEQAELEG KNAGSFDAFV AAYRAYTLNR FSV
//

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