(data stored in ACNUC7421 zone)

HOGENOM: BURCA_1_PE100

ID   BURCA_1_PE100                        STANDARD;      PRT;   372 AA.
AC   BURCA_1_PE100; Q1BZD9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Glutamate 5-kinase; EC=2.7.2 11;AltName:
DE   Full=Gamma-glutamyl kinase; Short=GK; (BURCA_1.PE100).
GN   Name=proB; OrderedLocusNames=Bcen_0102;
OS   BURKHOLDERIA CENOCEPACIA AU 1054.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=331271;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BURCA_1.PE100.
CC       Burkholderia cenocepacia AU 1054 chromosome 1, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:PROB_BURCA
CC   -!- FUNCTION: Catalyzes the transfer of a phosphate group to glutamate
CC       to form glutamate 5-phosphate which rapidly cyclizes to 5-
CC       oxoproline.
CC   -!- CATALYTIC ACTIVITY: ATP + L-glutamate = ADP + L-glutamate 5-
CC       phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-
CC       glutamate 5-semialdehyde from L-glutamate: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the glutamate 5-kinase family.
CC   -!- SIMILARITY: Contains 1 PUA domain.
CC   -!- GENE_FAMILY: HOG000246368 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q1BZD9; -.
DR   EMBL; CP000378; ABF75016.1; -; Genomic_DNA.
DR   RefSeq; YP_619989.1; NC_008060.1.
DR   ProteinModelPortal; Q1BZD9; -.
DR   STRING; Q1BZD9; -.
DR   GeneID; 4091864; -.
DR   GenomeReviews; CP000378_GR; Bcen_0102.
DR   KEGG; bcn:Bcen_0102; -.
DR   eggNOG; COG0263; -.
DR   OMA; TFGDNDM; -.
DR   ProtClustDB; PRK05429; -.
DR   BioCyc; BCEN331271:BCEN_0102-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004349; F:glutamate 5-kinase activity; IEA:EC.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00456; ProB; 1; -.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR001057; Glu/AcGlu_kinase.
DR   InterPro; IPR011529; Glu_5kinase.
DR   InterPro; IPR005715; Glu_5kinase/COase_Synthase.
DR   InterPro; IPR019797; Glutamate_5-kinase_CS.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_domain.
DR   Gene3D; G3DSA:3.40.1160.10; Aa_kinase; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   Pfam; PF01472; PUA; 1.
DR   PIRSF; PIRSF000729; GK; 1.
DR   PRINTS; PR00474; GLU5KINASE.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF53633; Aa_kinase; 1.
DR   SUPFAM; SSF88697; PUA-like; 1.
DR   TIGRFAMs; TIGR01027; ProB; 1.
DR   PROSITE; PS00902; GLUTAMATE_5_KINASE; 1.
DR   PROSITE; PS50890; PUA; 1.
DR   HOGENOMDNA; BURCA_1.PE100; -.
KW   gamma-glutamyl kinase;
KW   Amino-acid biosynthesis; ATP-binding; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Proline biosynthesis; Transferase.
SQ   SEQUENCE   372 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRSIIADSKR LVVKVGSSLV TNDGKGLDHA AIGRWAAQIA ALRAQGKEVV LVSSGAIAEG
     MQRLGWSKRP REIDELQAAA AVGQMGLAQV YESRFTEHGI RTAQILLTHA DLADRERYLN
     ARSTLLTLLR LGVVPIINEN DTVVTDEIKF GDNDTLGALV ANLIEGDALI ILTDQSGLFT
     ADPRKDPNAT LVGEANAGAP ELEAMAGGAG SSLGRGGMLT KILAAKRAAH SGANTVIASG
     READVLVRLA AGEAIGTQLI ARTARMAARK QWMADHLQVR GHVVIDAGAV EKLTAGGKSL
     LPIGVIDVQG AFARGEVIAC VGPDGREVAR GLTNYSSAET KLIHRKPSGE IETVLGYMLE
     PELIHRDNLV LV
//

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