(data stored in SCRATCH3701 zone)

HOGENOM6: BURCH_1_PE1039

ID   BURCH_1_PE1039                       STANDARD;      PRT;   867 AA.
AC   BURCH_1_PE1039; A0K5L6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (BURCH_1.PE1039).
GN   OrderedLocusNames=Bcen2424_1040;
OS   BURKHOLDERIA CENOCEPACIA HI2424.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=331272;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BURCH_1.PE1039.
CC       Burkholderia cenocepacia HI2424 chromosome 1, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A0K5L6_BURCH
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A0K5L6; -.
DR   EMBL; CP000458; ABK07793.1; -; Genomic_DNA.
DR   RefSeq; YP_834686.1; NC_008542.1.
DR   ProteinModelPortal; A0K5L6; -.
DR   SMR; A0K5L6; 30-530, 544-851.
DR   STRING; A0K5L6; -.
DR   GeneID; 4451085; -.
DR   GenomeReviews; CP000458_GR; Bcen2424_1040.
DR   KEGG; bch:Bcen2424_1040; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BURCH_1.PE1039; -.
DR   PRODOM; BURCH_1_PE1039.
DR   SWISS-2DPAGE; BURCH_1_PE1039.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   867 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDQFAKETLP TSLEEEMRRS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMHELNNDWN
     RAYKKSARIV GDVIGKYHPH GDTAVYDTIV RMAQDFSLRY MLIDGQGNFG SIDGDNAAAM
     RYTEIRMAKI GHELLADIDK ETVDFEPNYD GNEMQPSVLP SRIPNLLING SSGIAVGMAT
     NIPPHNLNEV VDACQHLLGN PEATIDELIE IIPAPDFPTA GIIYGVAGVR DGYRTGRGRV
     VMRAATHFEE IDRGQRMAII VDELPYQVNK RSLLERIAEL VNEKKLEGIS DIRDESDKSG
     MRVVIELKRG EVPEVVLNNL YKATQLQDTF GMNMVALVDG QPKLLNLKEI LQCFLSHRRE
     VLTRRTIYEL RKARERGHVL EGLAVALANI DEFIAIIKAA PTPPIAKQEL MAKPWDSSLV
     REMLTRAESE NAAAGGRSAY RPEGLNPAFG MQTDGLYRLS DTQAQEILQM RLQRLTGLEQ
     DKIIGEYRDV MAQIADLLDI LARPERITTM IGDELTSVKA EFGDARRSKI ELNATELNTE
     DLITPQDMVV TMSHAGYVKS QPLSEYRAQK RGGRGKQATQ MKEDDWIETL FIANTHDYIL
     CFSNRGRVYW VKVYEVPQGS RNSRGRPIVN MFPLQEGEKI NVVLPVKEFS ADKFIFMATS
     LGTVKKTPLE AFSRPMKKGI IAVGLDEGDY LIGASITDGA HDVMLFSDAG KAVRFDENDV
     RPMGREARGV RGMQLEDGQQ VIAMLVAGSE EQTVLTATEN GYGKRTPITE YTRHGRGTKG
     MIAIQTSERN GKVVAATLVD AEDQIMLITT AGVLIRTRVS EVREMGRATQ GVTLISLDEG
     TKLSGLQQIA EAEEGEGEAD EASDGEA
//

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