(data stored in SCRATCH3701 zone)

HOGENOM6: BURM1_2_PE2254

ID   BURM1_2_PE2254                       STANDARD;      PRT;   867 AA.
AC   BURM1_2_PE2254; A9ADW1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A;SubName: Full=DNA gyrase, A subunit;
DE   EC=5.99.1 3; (BURM1_2.PE2254).
GN   Name=gyrA; OrderedLocusNames=BMULJ_00975, Bmul_2264;
OS   BURKHOLDERIA MULTIVORANS ATCC 17616.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=395019;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BURM1_2.PE2254.
CC       Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A9ADW1_BURM1
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A9ADW1; -.
DR   EMBL; CP000868; ABX15949.1; -; Genomic_DNA.
DR   EMBL; AP009385; BAG42921.1; -; Genomic_DNA.
DR   RefSeq; YP_001580446.1; NC_010084.1.
DR   RefSeq; YP_001945457.1; NC_010804.1.
DR   ProteinModelPortal; A9ADW1; -.
DR   SMR; A9ADW1; 30-530, 544-851.
DR   STRING; A9ADW1; -.
DR   GeneID; 5766409; -.
DR   GeneID; 6357723; -.
DR   GenomeReviews; AP009385_GR; BMULJ_00975.
DR   GenomeReviews; CP000868_GR; Bmul_2264.
DR   KEGG; bmj:BMULJ_00975; -.
DR   KEGG; bmu:Bmul_2264; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BURM1_2.PE2254; -.
DR   PRODOM; BURM1_2_PE2254.
DR   SWISS-2DPAGE; BURM1_2_PE2254.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   867 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDQFAKETLP TSLEEEMRRS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMHELNNDWN
     RAYKKSARIV GDVIGKYHPH GDSAVYETIV RMAQDFSLRY MLVDGQGNFG SIDGDNAAAM
     RYTEIRMAKI GHELLADIDK ETVDFGPNYD GSEMQPLILP ARIPNLLING SSGIAVGMAT
     NIPPHNLNEV VDACQHLLNN PDATIDELIE IIPAPDFPTA GIIYGVAGVR DGYRTGRGRV
     VMRAATHFEE IDRGQRMAII VDELPYQVNK RSLLERIAEL VNEKKLEGIS DIRDESDKSG
     MRVVIELKRG EVPEVVLNNL YKATQLQDTF GMNMVALVDG QPKLLNLKEI LQCFLSHRRE
     VLTRRTVYEL RKARERGHVL EGLAVALANI DEFIAIIKAA PTPPIAKQEL MAKAWDSSLV
     REMLTRAEAE NAAAGGRAAY RPEGLNPAFG MQGDGLYKLS DTQAQEILQM RLQRLTGLEQ
     DKIIGEYRDV MAQISDLLDI LARPERITTM IGEELTTVKA EFGDARRSKI ELNATELNTE
     DLITPQDMVV TMSHAGYVKS QPLSEYRAQK RGGRGKQATQ MKEDDWIETL FIANTHDYML
     CFSNRGRVYW IKVYEVPQGS RNSRGRPIVN MFPLQDGEKI NVVLPVKEFS ADKFVFMATS
     LGTVKKTPLE AFSRPMKKGI IAVGLDEGDY LIGASITDGA HDVMLFSDAG KAVRFDENDV
     RPMGREARGV RGMQLDEGQQ VIALLVAGSE DQSVLTATEN GFGKRTPITE YTRHGRGTKG
     MIAIQTSERN GKVVAATLVD AEDQIMLITT AGVLIRTRVS EIREMGRATQ GVTLISLDEG
     TKLSGLQQIA EAEDGDGEAD EASDGEA
//

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