(data stored in ACNUC7421 zone)

HOGENOM: BURP6_1_PE1013

ID   BURP6_1_PE1013                       STANDARD;      PRT;   557 AA.
AC   BURP6_1_PE1013; A3N6U9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Dihydroxy-acid dehydratase; Short=DAD; EC=4.2.1 9;
DE   (BURP6_1.PE1013).
GN   Name=ilvD; OrderedLocusNames=BURPS668_1020;
OS   BURKHOLDERIA PSEUDOMALLEI 668.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=320373;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BURP6_1.PE1013.
CC       Burkholderia pseudomallei 668 chromosome I, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:ILVD_BURP6
CC   -!- CATALYTIC ACTIVITY: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-
CC       oxobutanoate + H(2)O.
CC   -!- COFACTOR: Binds 1 4Fe-4S cluster (Potential).
CC   -!- PATHWAY: Amino-acid biosynthesis; L-isoleucine biosynthesis; L-
CC       isoleucine from 2-oxobutanoate: step 3/4.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-valine biosynthesis; L-valine
CC       from pyruvate: step 3/4.
CC   -!- SIMILARITY: Belongs to the ilvD/edd family.
CC   -!- GENE_FAMILY: HOG000173155 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A3N6U9; -.
DR   EMBL; CP000570; ABN83258.1; -; Genomic_DNA.
DR   RefSeq; YP_001058070.1; NC_009074.1.
DR   ProteinModelPortal; A3N6U9; -.
DR   STRING; A3N6U9; -.
DR   GeneID; 4882532; -.
DR   GenomeReviews; CP000570_GR; BURPS668_1020.
DR   KEGG; bpd:BURPS668_1020; -.
DR   TIGR; BURPS668_1020; -.
DR   eggNOG; COG0129; -.
DR   OMA; NMPGAMI; -.
DR   ProtClustDB; PRK00911; -.
DR   BioCyc; BPSE320373:BURPS668_1020-MON; -.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00012; IlvD; 1; -.
DR   InterPro; IPR015928; Aconitase/3IPM_dehydase_swvl.
DR   InterPro; IPR004404; DihydroxyA_deHydtase.
DR   InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR   InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR   PANTHER; PTHR21000; ILVD_EDD_family; 1.
DR   Pfam; PF00920; ILVD_EDD; 1.
DR   SUPFAM; SSF52016; Aconitase/3IPM_dehydase_swvl; 1.
DR   TIGRFAMs; TIGR00110; IlvD; 1.
DR   PROSITE; PS00886; ILVD_EDD_1; 1.
DR   PROSITE; PS00887; ILVD_EDD_2; 1.
DR   HOGENOMDNA; BURP6_1.PE1013; -.
KW   4Fe-4S; Amino-acid biosynthesis;
KW   Branched-chain amino acid biosynthesis; Complete proteome; Iron;
KW   Iron-sulfur; Lyase; Metal-binding.
SQ   SEQUENCE   557 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSYNRRSKNI TQGVARSPNR SMYYALGYQK EDFDKPMIGI ANGHSTITPC NAGLQRLSDA
     AVAAVKDAGA NPQIFGTPTI SDGMSMGTEG MKYSLVSREV IADCIETCVQ GQWMDGVVVV
     GGCDKNMPGG MIALARINVP GIYVYGGTIR PGHWKGHDLT IVSSFEAVGE FTAGRMSQED
     FEGVEKNACP TTGSCGGMYT ANTMSSSFEA LGMSLLYSST MANPDQEKVD SAAESARVLV
     EAVKKDLKPR DIITKQSIEN AVSVIMATGG STNAVLHYLA IAHAAEIDWS IEDFERIRKR
     VPVICDLKPS GQYVATDLHA AGGIPQVMKL LLDAGLLHGD CMTITGRTLA EELKDVPSVP
     RADQKVIHPI DQALYKEGHL AILKGNLAED GAVAKITGLK NPVITGPARV FDDEQSALAA
     ILDDRIRAGD VVVLRYLGPQ GGPGMPEMLA PTSAIIGKGL GESVGLITDG RFSGGTWGMV
     VGHVAPEAFV GGTIALVQEG DSITIDAHKL LLQLNVDDAE LARRRAAWKQ PAPRYTRGVL
     AKYAALARPA NQGAVTG
//

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