(data stored in SCRATCH3701 zone)

HOGENOM6: BURP8_1_PE730

ID   BURP8_1_PE730                        STANDARD;      PRT;   859 AA.
AC   BURP8_1_PE730; B2JEZ8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (BURP8_1.PE730).
GN   OrderedLocusNames=Bphy_0738;
OS   BURKHOLDERIA PHYMATUM STM815.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=391038;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BURP8_1.PE730.
CC       Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:B2JEZ8_BURP8
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B2JEZ8; -.
DR   EMBL; CP001043; ACC69927.1; -; Genomic_DNA.
DR   RefSeq; YP_001856973.1; NC_010622.1.
DR   STRING; B2JEZ8; -.
DR   GeneID; 6242236; -.
DR   GenomeReviews; CP001043_GR; Bphy_0738.
DR   KEGG; bph:Bphy_0738; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BURP8_1.PE730; -.
DR   PRODOM; BURP8_1_PE730.
DR   SWISS-2DPAGE; BURP8_1_PE730.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   859 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRRSYIEYAM SVIVGRALPD VRDGLKPVHR RVLYAMHELN NDWNRAYKKS ARIVGDVIGK
     YHPHGDSAVY DTIVRMAQDF SLRYMLVDGQ GNFGSVDGDN AAAMRYTEIR MAKIGHELLA
     DIDKETVDFQ PNYDGSENEP SILPARIPNL LINGSSGIAV GMATNIPPHN LSEIVDACHH
     LLKNPEASID ELIEIVPAPD FPTAGIIYGV AGVRDGYRTG RGRVVMRAAT HFEEIDRGQR
     MAIIVDELPY QVNKRSLLER IAELVNEKKL EGISDIRDES DKSGMRVVIE LKRGEVPEVI
     LNNLYKATQL QDTFGMNMVA LVDGQPKLLN LKEMLSHFLS HRREVLTRRT VYELRKARER
     GHVLEGLAVA LANIDDFIAI IKAAPTPPIA KQELMDRSWD SSIVREMLQR AETDNATSGG
     RAAYRPEGLN PAYGMQADGL YRLSDTQAQE ILQMRLQRLT GLEQDKIIGE YRDVMAQIAD
     LLDILARPER ITSIIFDELT TIKSEFGDER RSKIEMNATE LNTEDLITPQ DMVVTMSHSG
     YVKSQPLSEY RAQKRGGRGK QATQMKEDDW IDTLFIANTH DHILCFSNRG RVYWLKVYEV
     PQGSRNSRGR PIVNMFPLQE GEKITVVLPV KEFSADKFVF MATALGTVKK TPLEAFSRPL
     KKGIIAVGLD DGDYLIGAAI TDGEHDVMLF SDSGKAVRFD ENDVRPMGRE ARGVRGMQLE
     DGQSVIALLV AGDEQQSVLT ATENGYGKRT PITEYTRHGR GTKGMIAIQT SERNGKVVAA
     TLVDPEAQIM LITNTGVLIR TRVSEIREMG RATQGVTLIS LDEGTKLSGL QQIAEAEADV
     DGDADLPADE AGGDESEAS
//

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