(data stored in SCRATCH3701 zone)

HOGENOM6: BURSG_1_PE2552

ID   BURSG_1_PE2552                       STANDARD;      PRT;   862 AA.
AC   BURSG_1_PE2552; E1T6A3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (BURSG_1.PE2552).
GN   OrderedLocusNames=BC1003_2608;
OS   BURKHOLDERIA SP. CCGE1003.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=640512;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BURSG_1.PE2552.
CC       Burkholderia sp. CCGE1003 chromosome chromosome 1, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:E1T6A3_BURSG
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E1T6A3; -.
DR   EMBL; CP002217; ADN58561.1; -; Genomic_DNA.
DR   RefSeq; YP_003907852.1; NC_014539.1.
DR   GeneID; 9767511; -.
DR   GenomeReviews; CP002217_GR; BC1003_2608.
DR   KEGG; bgf:BC1003_2608; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BURSG_1.PE2552; -.
DR   PRODOM; BURSG_1_PE2552.
DR   SWISS-2DPAGE; BURSG_1_PE2552.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   862 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRRSYLDYAM SVIVGRALPD VRDGLKPVHR RVLYAMHELN NDWNRAYKKS ARIVGDVIGK
     YHPHGDTAVY DTIVRMAQDF SLRYMLVDGQ GNFGSVDGDN AAAMRYTEIR MAKIGHELLA
     DIDKETVDFT PNYDGSENEP AILPARIPNL LINGSSGIAV GMATNIPPHN LNEVVDACQH
     LLKNPDASID ELIEIVPAPD FPTAGIIYGV AGVRDGYRTG RGRVVMRALT HFEEIDRGQR
     MAIIVDELPY QVNKRSLLER IAELVNEKKL EGISDIRDES DKSGMRVVIE LKRGEVPEVV
     LNNLYKATQL QDTFGMNMVA LVDGQPKLLN LKEMLSCFLS HRREVLTRRT VYELRKARER
     GHVLEGLAVA LANIDEFIAI IKAAPTPPIA KQELMARPWD SSLVREMLSR AETENASAGG
     REAYRPDGLN PSFGMQADGL YRLSDTQAQE ILQMRLQRLT GLEQDKIIGE YRDVMAQIAD
     LLDILARPER ITAIIVDELT SIKAEFGDAR RSKIELNATE LNTEDLITPQ EMVVTMSHAG
     YVKSQPLSEY RAQKRGGRGK QATSMKEDDW IDTLFIANTH DHILCFSNRG RVYWVKVYEV
     PQGSRNSRGR PIVNMFPLQE GEKITVVLPV KEFSADKFVF MATALGTVKK TPLEAFSRPL
     RKGIIAVGLD DGDYLIGAAI TDGQHDVMLF SDSGKAVRFD ENDVRPMGRE ARGVRGMQLE
     DGQNVIALLV AGDEQQSVLT ATENGFGKRT PITEYTRHGR GTKGMIAIQT SERNGKVVAA
     TLVDPEAQIM LITTTGVLIR TRVSEIREMG RATQGVTLIS LDEGTKLSGL QQVAEAEAEG
     DLEGDAEGPA ESGNGGEDGG AA
//

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