(data stored in SCRATCH3701 zone)

HOGENOM6: BURXL_1_PE3435

ID   BURXL_1_PE3435                       STANDARD;      PRT;   882 AA.
AC   BURXL_1_PE3435; Q13VB6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (BURXL_1.PE3435).
GN   OrderedLocusNames=Bxeno_A3435; ORFNames=Bxe_A0974;
OS   BURKHOLDERIA XENOVORANS LB400.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=266265;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS BURXL_1.PE3435.
CC       Burkholderia xenovorans LB400 chromosome 1, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q13VB6_BURXL
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q13VB6; -.
DR   EMBL; CP000270; ABE31973.1; -; Genomic_DNA.
DR   RefSeq; YP_560025.1; NC_007951.1.
DR   ProteinModelPortal; Q13VB6; -.
DR   SMR; Q13VB6; 30-530, 544-851.
DR   STRING; Q13VB6; -.
DR   GeneID; 4003040; -.
DR   GenomeReviews; CP000270_GR; Bxeno_A3435.
DR   KEGG; bxe:Bxe_A0974; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; BURXL_1.PE3435; -.
DR   PRODOM; BURXL_1_PE3435.
DR   SWISS-2DPAGE; BURXL_1_PE3435.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   882 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDQFAKETLP ISLEEEMRRS YLDYAMSVIV GRALPDVRDG LKPVHRRVLY AMHELNNDWN
     RAYKKSARIV GDVIGKYHPH GDTAVYDTIV RMAQDFSLRY MLVDGQGNFG SVDGDNAAAM
     RYTEIRMAKI GHELLADIDK ETVDFTPNYD GSENEPAILP ARIPNLLING SSGIAVGMAT
     NIPPHNLNEV VDACQHLLKN PEATIDELIE IVPAPDFPTA GIIYGVAGVR DGYRTGRGRV
     VMRALTHFEE IDRGQRMAII VDELPYQVNK RSLLERIAEL VNEKKLEGIS DIRDESDKSG
     MRVVIELKRG EVPEVVLNNL YKATQLQDTF GMNMVALVDG QPKLLNLKEM LSCFLSHRRE
     VLTRRTVYEL RKARERGHVL EGLAVALANI DEFIAIIKAA PTPPIAKQEL MARAWDSSLV
     REMLSRAETE NATAGGREAY RPDGLNPSFG MQSDGLYRLS DTQAQEILQM RLQRLTGLEQ
     DKIIGEYREV MAQIADLLDI LARPERITAI IVEELTSIKA EFGDARRSKI ELNATELNTE
     DLITPQEMVV TMSHAGYVKS QPLSEYSAQK RGGRGKQATA MKEDDWIDTL FIANTHDHIL
     CFSNRGRVYS VKVYEVPQGS RNSRGRPIIN IFPLQEGEKI TVVLPVKEFS ADKFVFMGTA
     LGTVKKTPLE AFGRVLRKGI IAVGLDDGDY LIGAAITDGQ HDVMLFSDSG KAVRFDENDV
     RPMGREARGV RGMQLEDGQN VIALLVAGDE QQSVLTATEN GFGKRTPIIE YTRHGRGTKG
     MIAIQTSERN GKVVAATLVD QEAQIMLITN TGVLIRTRVS EIREMGRATQ GVTLISLDEG
     TKLSGLQQVA EAEAEGDAES DAEGPAEGNN AGDNGGEEGG AA
//

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