(data stored in ACNUC5448 zone)

HOGENOM: CABRI1_6_PE807

ID   CABRI1_6_PE807                       STANDARD;      PRT;   2099 AA.
AC   CABRI1_6_PE807; Q622K8; A8WS20;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Unconventional myosin heavy chain 6; (CABRI1_6.PE807).
GN   Name=hum-6; ORFNames=CBG02140;
OS   CAENORHABDITIS BRIGGSAE AF16.
OC   Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;
OC   Rhabditidae; Peloderinae; Caenorhabditis.
OX   NCBI_TaxID=473542;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CABRI1_6.PE807.
CC       Caenorhabditis briggsae (strain AF16) chromosome X, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:HUM6_CAEBR
CC   -!- FUNCTION: Myosins are actin-based motor molecules with ATPase
CC       activity. Unconventional myosins serve in intracellular movements.
CC       Their highly divergent tails are presumed to bind to membranous
CC       compartments, which would be moved relative to actin filaments (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Contains 2 FERM domains.
CC   -!- SIMILARITY: Contains 3 IQ domains.
CC   -!- SIMILARITY: Contains 1 myosin head-like domain.
CC   -!- SIMILARITY: Contains 2 MyTH4 domains.
CC   -!- SIMILARITY: Contains 1 Ras-associating domain.
CC   -!- GENE_FAMILY: HOG000007836 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q622K8; A8WS20; -.
DR   EMBL; CAAC02000448; CAP23278.3; -; Genomic_DNA.
DR   RefSeq; XP_002643889.1; XM_002643843.1.
DR   HSSP; P08799; 1MND.
DR   ProteinModelPortal; Q622K8; -.
DR   GeneID; 8585882; -.
DR   KEGG; cbr:CBG02140; -.
DR   CTD; 8585882; -.
DR   WormBase; CBG02140; CBP06188; WBGene00025248; Cbr-hum-6.
DR   OMA; EMSAKKA; -.
DR   PhylomeDB; Q622K8; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; ISS:UniProtKB.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR001609; Myosin_head_motor_dom.
DR   InterPro; IPR000857; MyTH4_dom.
DR   InterPro; IPR011993; PH_type.
DR   Gene3D; G3DSA:1.20.80.10; ACBP; 2.
DR   Gene3D; G3DSA:2.30.29.30; PH_type; 1.
DR   Pfam; PF00373; FERM_M; 2.
DR   Pfam; PF09379; FERM_N; 1.
DR   Pfam; PF00612; IQ; 2.
DR   Pfam; PF00063; Myosin_head; 1.
DR   Pfam; PF00784; MyTH4; 2.
DR   PRINTS; PR00193; MYOSINHEAVY.
DR   SMART; SM00295; B41; 2.
DR   SMART; SM00015; IQ; 3.
DR   SMART; SM00242; MYSc; 1.
DR   SMART; SM00139; MyTH4; 2.
DR   SUPFAM; SSF47031; FERM_3-hlx; 2.
DR   PROSITE; PS00660; FERM_1; FALSE_NEG.
DR   PROSITE; PS00661; FERM_2; FALSE_NEG.
DR   PROSITE; PS50057; FERM_3; 2.
DR   PROSITE; PS50096; IQ; 3.
DR   PROSITE; PS51016; MYTH4; 2.
DR   PROSITE; PS50200; RA; FALSE_NEG.
DR   HOGENOMDNA; CABRI1_6.PE807; -.
KW   CAP23278.300200367fold_1320000031;
KW   Unconventional myosin heavy chain 6 ;
KW   Actin-binding; ATP-binding; Coiled coil; Complete proteome; Cytoplasm;
KW   Motor protein; Myosin; Nucleotide-binding; Reference proteome; Repeat.
SQ   SEQUENCE   2099 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVLVSKGDFI WIEPGKAEGS IPIGARVIDQ DHGRLKVIDD LGNEQWLSAD RRVRLMHPTS
     VQGVEDMCQL GDFHESAILR NLFIRYREKL IYAYTGSILI AVNPYMDIAI YTADEIRMYK
     RKRIGELPPH IFAIADNAYT NMRREKKNQS VIISGESGAG KTESTKLVLQ FLATISGQHS
     WIEQQVLEAN PVLEAFGNAK TIRNDNSSRF GKYIDVHFNE SGSIEGAKIE QYLLEKSRIV
     TQSENERNYH IFYCLLAGLS KEEKMELELG TAADYYYLIQ GKTLTAEGRD DAADLAEIRS
     AMRVLMINEQ EIGSIFKLLA ALLHIGNIRF RQNTTDNMES VDVADPSTLV RIAKLLNLHE
     QNLLDAITTK SLVTREERVI SRLNGQQAID ARDALAKAIY GKLFIHIVRR VNDAIYKPSQ
     SIRTSIGILD IFGFENFESN SFEQLCINFA NETLQQFFVQ HVFKMEQKEY DEENINWRHI
     KFVDNQATVD LIAQRPMNIL SLIDEESIFP KGTDKTMLLK LHSTHGRNEL YLQPKSELQR
     AFGVTHFAGS VFYNTRGFLE KNRDSFSGDL SALISSSKMP FLARLFDDLE YDTSSRKKVT
     VGNQFRRSLE QLMTQLTQTH PFFIRCIKPN ELKRALVMDR DLVLRQLRYS GMMETIKIRR
     SGYPIRHDYY PFVFRYRVLV SSIRGPANRI DLHDAAKKIC HKVLGPNADY QLGKTKVFLK
     DKHDLVLEQE YYRILKDKAV IIQKNVRRWL VRKDFEKQRQ AAVTIQTAWR GYDQRKRYRQ
     IISGFSRLQA VLRSRQLVSH YQSLRKTIIQ FQAVCRGTLL RRQVGEMRRR GEKAPLTEVS
     STASVISDSH EEELVSHLFD FLPSDGKDSG NENDSTDSSR RGSYSRLHPS PVMPPTNIPR
     VDSFIDEDLS KFQFGKYAAT FFQAQATATH IKKPIKTALL THTEPSAQLA ALASWTTILR
     FMGDLSDVKP GSTNGSEIYD KTPVMSRLYA TLGKKFSTRD VEEALLSSEY GGNKTLKKGM
     GKKLISMTLK RKGKIGGSDT SSISSDSAYS GFNAMLENKP MTSLDKLHYI IGLGILREDL
     RDEIYCQLCK QLSNNPSKLS AARGWILLSL CVGCFAPSER FIKYLFCFIR ERGPAGTGYS
     TYIEDRLRRT QVNGTRHQPP SYVELQANKS QKPVVLAVTF MDGSVKTLCA DSATTASELC
     KQLAEKVGLT NSFGFSLYIA LFDKVSSLGS GTDHVMDAIS QCEQYAKEQG RQERNAPWRL
     FFRKEIFSPW HDPKDDAVST NLIYQQVIRG IKYGEYRCDK DEELAAICAQ QYYIDEGTMD
     VNKLENNLAS YLPDFEMAGK DMALEKWTQT IMHQYRKKFT GRLPSQIEVK EDVVSIAKTK
     WPLLFSRFYE ALKFAGPPLP KNEVIIAVNW TGVYVVDDRE HVMLEFSFPE ISTAYYGKGK
     RSTTDTCTIR SVVGDEYTFQ SPNADDITNL IVLFLEGLKK RSRYLVAIKA QKGDEKNNFL
     DFEKGDLLIL VNEFTGNTLL TESVVKGENS RTCLFGLIRA ENVYVLPTLV KPSKNTLQIF
     PKDMDMSLDL FNNNKQVTVI DYNAEPYTLE NFAEDNFNSQ VKRVGSQISL MTLRKKESQI
     ESWRFSRDHI EHPLLKKLNG RDDACRGAVE IFAAIMKYMG DEPSKRSRLG THLTDHIFKL
     PISMEALRDE LYCQLVKQLT LNPSIMSEEK GWELLWMATG LFAPSAALAK EISHFLKSRP
     HPIALDCQNR MQKLAKGGSR KYPPHLVEVE AIQHKTTQIF HKVFFPDKTD EAIEVDSATR
     ARDFCHKIGY RLGLKSSDGF SLFVKIKDKV LAVPETEFFF DYVRSLSDWV HTNHAMQKDS
     TMIPINYQVY FMRKLWFNFV PGADSQADII FHYHQESQKY LLGYHKTTKN DVIELAALIL
     RAMTKEGKNA PLAQIPQLLD DIVPKDSLKM CSASEWRKTI SNAYARVEHL KPDQAKIEFL
     KYICRWPTFG SAFFPVSQYS DLSLPDRLLL AINQTGVNIY HLESKNLLVQ YPFNVICNWT
     SGNTYFNMTV GNMLKGNEGK KLLLDTTVGY KMDDLLTSYI SLLISNQTNQ PSKHREVAL
//

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