(data stored in SCRATCH9089 zone)

HOGENOM6: CACRE1_1_PE1557

ID   CACRE1_1_PE1557                      STANDARD;      PRT;   759 AA.
AC   CACRE1_1_PE1557; O54478;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase 4 subunit A; EC=5.99.1 -;AltName:
DE   Full=Topoisomerase IV subunit A; (CACRE1_1.PE1557).
GN   Name=parC; OrderedLocusNames=CC_1566;
OS   CAULOBACTER CRESCENTUS CB15.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CACRE1_1.PE1557.
CC       Caulobacter crescentus CB15, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:PARC_CAUCR
CC   -!- FUNCTION: Topoisomerase IV is essential for chromosome
CC       segregation. It relaxes supercoiled DNA. Performs the decatenation
CC       events required during the replication of a circular DNA molecule
CC       (By similarity).
CC   -!- SUBUNIT: Composed of two subunits: ParC and ParE.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076277 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; O54478; -.
DR   EMBL; U94696; AAC38043.1; -; Genomic_DNA.
DR   EMBL; U86302; AAF14339.1; -; Genomic_DNA.
DR   EMBL; AE005673; AAK23545.1; -; Genomic_DNA.
DR   PIR; E87443; E87443.
DR   RefSeq; NP_420377.1; NC_002696.2.
DR   ProteinModelPortal; O54478; -.
DR   GeneID; 941333; -.
DR   GenomeReviews; AE005673_GR; CC_1566.
DR   KEGG; ccr:CC_1566; -.
DR   NMPDR; fig|190650.1.peg.1557; -.
DR   TIGR; CC_1566; -.
DR   OMA; HNAAELC; -.
DR   ProtClustDB; PRK05561; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   InterPro; IPR005742; TopoIV_A_Gneg.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 2.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01062; ParC_Gneg; 1.
DR   HOGENOMDNA; CACRE1_1.PE1557; -.
DR   PRODOM; CACRE1_1_PE1557.
DR   SWISS-2DPAGE; CACRE1_1_PE1557.
KW   DNA topoisomerase IV subunit A;
KW   Cell membrane; Complete proteome; DNA-binding; Isomerase; Membrane;
KW   Reference proteome; Topoisomerase.
SQ   SEQUENCE   759 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNKPVLPPPG GPDDGDRILD EPLTEALSRR YLAYALSTIG SRALPDVRDG LKPVHRRVLY
     AMSNMRLNPD AAARKCAKVV GEVMGNFHPH GDASIYDALV RLAQEFSQRI PLVEGQGNFG
     NIDGDSAAAM RYTECKMTEA AMLLLDGIDE DAVDFRPTYD GQDEEPVVLP SGFPNLLANG
     SSGIAVGMAT SIPPHNAAEL IDACQLLLAN PDATTADLLE KVPGPDFPTG GVIVESRASL
     LETYETGRGG VRMRAKWEKE DTGRGTYQIV VTEIPYQVKK SDLVEQLADL IDSKKAALLG
     DVRDESAEDI RLVLEPKSKN VEPEVLMESL FKLSALESRF PVNINVLDAR GTPGVMGIKQ
     ALMAFLAHRR EVLTRRARHR LAKIEARLHI LDGLLIAYLN LDEVIRIVRY EDKPKEKLIE
     TFGLTDIQAD AILNTRLRQL AKLEEMEIRR EHAELVEERD GILAMLASEA KQWKLVGVGL
     SEVRAALLKI KHPLDKPRPT GVTGRSVFGE APQVDADAAI EAMIVREPIT IILSERGWIR
     AAKGKIDDPS ELKFKEGDKL GFLVPAETTD KLLIFSSDGR FFTLGCDKLP SARGHGEPVR
     MMIELDDKVK IIDVFPFKAG RKRILASKGG YGFLMPEEEA LANRKAGKQV LNVGNEGAAF
     CLEAVGDQLA VIGDNGKILI FPLEELPEMP RGKGVKLQAY REGGLRDGLS FNAETGAYWI
     DTAGRRRDWA EWKEWVGRRA GAGKLVPKGF ATNKRFRPK
//

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