(data stored in ACNUC7421 zone)

HOGENOM: CACRE1_1_PE280

ID   CACRE1_1_PE280                       STANDARD;      PRT;   283 AA.
AC   CACRE1_1_PE280; Q9ABE7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
DE   N-succinyltransferase; EC=2.3.1 117;AltName: Full=Tetrahydrodipicolinate
DE   N-succinyltransferase; Short=THDP succinyltransferase; Short=THP
DE   succinyltransferase; Short=Tetrahydropicolinate succinylase;
DE   (CACRE1_1.PE280).
GN   Name=dapD; OrderedLocusNames=CC_0281;
OS   CAULOBACTER CRESCENTUS CB15.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CACRE1_1.PE280.
CC       Caulobacter crescentus CB15, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:DAPD_CAUCR
CC   -!- CATALYTIC ACTIVITY: Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-
CC       2,6-dicarboxylate + H(2)O = CoA + N-succinyl-L-2-amino-6-
CC       oxoheptanedioate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate
CC       (succinylase route): step 1/3.
CC   -!- SUBUNIT: Homotrimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK22268.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000003295 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q9ABE7; -.
DR   EMBL; AE005673; AAK22268.1; ALT_INIT; Genomic_DNA.
DR   PIR; H87283; H87283.
DR   RefSeq; NP_419100.1; NC_002696.2.
DR   ProteinModelPortal; Q9ABE7; -.
DR   GeneID; 942366; -.
DR   GenomeReviews; AE005673_GR; CC_0281.
DR   KEGG; ccr:CC_0281; -.
DR   NMPDR; fig|190650.1.peg.280; -.
DR   TIGR; CC_0281; -.
DR   OMA; KAILLYF; -.
DR   ProtClustDB; PRK11830; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008666; F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity; IEA:EC.
DR   GO; GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00811; DapD; 1; -.
DR   InterPro; IPR005664; DapD.
DR   InterPro; IPR001451; Hexapep_transf.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR023180; THP_succinylTrfase_dom1.
DR   InterPro; IPR011004; Trimer_LpxA-like.
DR   Gene3D; G3DSA:1.10.166.10; THP_succinylTrfase_dom1; 1.
DR   Pfam; PF00132; Hexapep; 2.
DR   SUPFAM; SSF51161; Trimer_LpxA_like; 1.
DR   TIGRFAMs; TIGR00965; DapD; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
DR   HOGENOMDNA; CACRE1_1.PE280; -.
KW   Acyltransferase; Amino-acid biosynthesis; Complete proteome;
KW   Cytoplasm; Diaminopimelate biosynthesis; Lysine biosynthesis;
KW   Reference proteome; Repeat; Transferase.
SQ   SEQUENCE   283 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSLPPVSLAD LQTEIEAAWE ARADISAATT GPVRTAVDEA LRLLDSGEAR VAEKIDGEWF
     THQWLKKAVL LSFRLNPNTV MRSGALGGGV GPWWDKVPNK FDGWDAPQFE AGGFRAVPGA
     IVRRGAHIGK NVILMPSFVN IGGYVDEGTM VDTWVTVGSC AQIGKNVHLS GGVGIGGVLE
     PLQANPTIIE DNCFIGARSE VVEGVVVGEG SVLSMGVFIS ASTKIVDRKT GAVHIGKVPP
     YSVVVPGNLP DPNGGPGLYC AVIVKTVDAQ TRSKTSINDL LRD
//

If you have problems or comments...

PBIL Back to PBIL home page