(data stored in ACNUC16935 zone)

HOGENOM: CAEELIII_PE3808

ID   CAEELIII_PE3808                      STANDARD;      PRT;   128 AA.
AC   CAEELIII_PE3808; P49632; P14792; Q9U1P3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ubiquitin-60S ribosomal protein L40;AltName:
DE   Full=CEP52;Contains: RecName: Full=Ubiquitin;Contains: RecName: Full=60S
DE   ribosomal protein L40;Flags: Precursor; (CAEELIII.PE3808).
GN   Name=ubq-2; Synonyms=ubib; ORFNames=ZK1010.1;
OS   CAENORHABDITIS ELEGANS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Pseudocoelomata; Nematoda;
OC   Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CAEELIII.PE3808.
CC       Caenorhabditis elegans chromosome III WS210  sequence 1..13783685
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RL40_CAEEL
CC   -!- FUNCTION: Ubiquitin exists either covalently attached to another
CC       protein, or free (unanchored). When covalently bound, it is
CC       conjugated to target proteins via an isopeptide bond either as a
CC       monomer (monoubiquitin), a polymer linked via different Lys
CC       residues of the ubiquitin (polyubiquitin chains) or a linear
CC       polymer linked via the initiator Met of the ubiquitin (linear
CC       polyubiquitin chains). Polyubiquitin chains, when attached to a
CC       target protein, have different functions depending on the Lys
CC       residue of the ubiquitin that is linked: Lys-48-linked is involved
CC       in protein degradation via the proteasome. Linear polymer chains
CC       formed via attachment by the initiator Met lead to cell signaling.
CC       Ubiquitin is usually conjugated to Lys residues of target
CC       proteins, however, in rare cases, conjugation to Cys or Ser
CC       residues has been observed. When polyubiquitin is free
CC       (unanchored-polyubiquitin), it also has distinct roles, such as in
CC       activation of protein kinases, and in signaling (By similarity).
CC   -!- FUNCTION: Ribosomal protein L40 is a component of the 60S subunit
CC       of the ribosome.
CC   -!- SUBUNIT: Ribosomal protein L40 is part of the 60S ribosomal
CC       subunit (By similarity).
CC   -!- SUBCELLULAR LOCATION: Ubiquitin: Cytoplasm (By similarity).
CC       Nucleus (By similarity).
CC   -!- SUBCELLULAR LOCATION: 60S ribosomal protein L40: Cytoplasm (By
CC       similarity).
CC   -!- MISCELLANEOUS: In C.elegans ubiquitin is encoded by 2 different
CC       genes. ubq-2 gene codes for a single copy of ubiquitin fused to
CC       the ribosomal proteins L40. ubq-1 gene codes for a polyubiquitin
CC       precursor with exact head to tail repeats.
CC   -!- MISCELLANEOUS: For a better understanding, features related to
CC       ubiquitin are only indicated for the first chain.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the ubiquitin
CC       family.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the ribosomal
CC       protein L40e family.
CC   -!- SIMILARITY: Contains 1 ubiquitin-like domain.
CC   -!- GENE_FAMILY: HOG000233942 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Caenorhabditis_elegans;ZK1010.1;ZK1010.1.2;ZK1010.1.2.
DR   EMBL; L31492; - ;
DR   EMBL; M21321; - ;
DR   EMBL; M23433; - ;
DR   EMBL; U23172; - ;
DR   EMBL; Z82083; - ;
DR   UniProtKB/Swiss-Prot; P49632; P14792; Q9U1P3; -.
DR   EMBL; L31492; AAC37252.1; -; Genomic_DNA.
DR   EMBL; Z82083; CAB04967.1; -; Genomic_DNA.
DR   PIR; T27638; T27638.
DR   RefSeq; NP_499695.1; NM_067294.2.
DR   UniGene; Cel.8282; -.
DR   ProteinModelPortal; P49632; -.
DR   SMR; P49632; 1-76, 89-128.
DR   STRING; P49632; -.
DR   EnsemblMetazoa; ZK1010.1.1; ZK1010.1.1; ZK1010.1.
DR   EnsemblMetazoa; ZK1010.1.2; ZK1010.1.2; ZK1010.1.
DR   GeneID; 176718; -.
DR   KEGG; cel:ZK1010.1; -.
DR   UCSC; ZK1010.1.1; c. elegans.
DR   CTD; 176718; -.
DR   WormBase; ZK1010.1; CE15495; WBGene00006728; ubq-2.
DR   GeneTree; EMGT00050000005052; -.
DR   OMA; YNCEKMI; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.
DR   GO; GO:0040007; P:growth; IMP:WormBase.
DR   GO; GO:0002119; P:nematode larval development; IMP:WormBase.
DR   GO; GO:0000003; P:reproduction; IMP:WormBase.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   InterPro; IPR001975; Ribosomal_L40e.
DR   InterPro; IPR000626; Ubiquitin.
DR   InterPro; IPR019954; Ubiquitin_CS.
DR   InterPro; IPR019956; Ubiquitin_subgr.
DR   InterPro; IPR019955; Ubiquitin_supergroup.
DR   Pfam; PF01020; Ribosomal_L40e; 1.
DR   Pfam; PF00240; ubiquitin; 1.
DR   PRINTS; PR00348; UBIQUITIN.
DR   SMART; SM00213; UBQ; 1.
DR   PROSITE; PS00299; UBIQUITIN_1; 1.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
DR   HOGENOMDNA; CAEELIII.PE3808; -.
KW   ZK1010.13110200367fold_1320000031; ZK1010.1.211110.62fold_1320000031;
KW   UBIQ_CAEEL; L31492; M21321; M23433; U23172; Z82083;
KW   Complete proteome; Cytoplasm; Isopeptide bond; Nucleus;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Ubl conjugation.
SQ   SEQUENCE   128 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQIFVKTLTG KTITLEVEAS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN
     IQKESTLHLV LRLRGGIIEP SLRQLAQKYN CDKQICRKCY ARLPPRASNC RKKKCGHSSE
     LRIKKKLK
//

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