(data stored in ACNUC32233 zone)

HOGENOM: CAEELV_PE1966

ID   CAEELV_PE1966                        STANDARD;      PRT;   2302 AA.
AC   CAEELV_PE1966; Q95ZL8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Uncoordinated protein 70, isoform b, confirmed by
DE   transcript evidence; (CAEELV.PE1966).
GN   Name=unc-70; ORFNames=K11C4.3;
OS   CAENORHABDITIS ELEGANS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Pseudocoelomata; Nematoda;
OC   Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CAEELV.PE1966.
CC       Caenorhabditis elegans chromosome V WS210  sequence 1..20924143
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q95ZL8_CAEEL
CC   -!- SIMILARITY: Contains 1 PH domain.
CC   -!- GENE_FAMILY: HOG000007281 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Caenorhabditis_elegans;K11C4.3;K11C4.3B;K11C4.3B.
DR   EMBL; AF166169; - ;
DR   EMBL; U64854; - ;
DR   UniProtKB/Swiss-Prot; Q95ZL8; -.
DR   EMBL; U64854; AAK77612.2; -; Genomic_DNA.
DR   RefSeq; NP_001024053.1; NM_001028882.1.
DR   UniGene; Cel.18368; -.
DR   HSSP; Q01082; 1BKR.
DR   ProteinModelPortal; Q95ZL8; -.
DR   SMR; Q95ZL8; 35-269, 283-2078, 2161-2274.
DR   STRING; Q95ZL8; -.
DR   PRIDE; Q95ZL8; -.
DR   EnsemblMetazoa; K11C4.3b; K11C4.3b; K11C4.3.
DR   GeneID; 179077; -.
DR   KEGG; cel:K11C4.3; -.
DR   NMPDR; fig|6239.3.peg.18279; -.
DR   UCSC; K11C4.3a; c. elegans.
DR   CTD; 179077; -.
DR   WormBase; K11C4.3b; CE30159; WBGene00006803; unc-70.
DR   eggNOG; meNOG05002; -.
DR   InParanoid; Q95ZL8; -.
DR   OMA; KEGEDMI; -.
DR   PhylomeDB; Q95ZL8; -.
DR   NextBio; 903816; -.
DR   ArrayExpress; Q95ZL8; -.
DR   GO; GO:0030054; C:cell junction; IDA:WormBase.
DR   GO; GO:0031674; C:I band; IDA:WormBase.
DR   GO; GO:0016328; C:lateral plasma membrane; IDA:WormBase.
DR   GO; GO:0031430; C:M band; IDA:WormBase.
DR   GO; GO:0008091; C:spectrin; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IMP:WormBase.
DR   GO; GO:0007413; P:axonal fasciculation; IMP:WormBase.
DR   GO; GO:0016358; P:dendrite development; IMP:WormBase.
DR   GO; GO:0010172; P:embryonic body morphogenesis; IGI:WormBase.
DR   GO; GO:0046716; P:muscle cell homeostasis; IMP:WormBase.
DR   GO; GO:0002119; P:nematode larval development; IMP:WormBase.
DR   GO; GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
DR   GO; GO:0040017; P:positive regulation of locomotion; IMP:WormBase.
DR   InterPro; IPR001589; Actinin_actin-bd_CS.
DR   InterPro; IPR001715; CH-domain.
DR   InterPro; IPR011993; PH_type.
DR   InterPro; IPR001849; Pleckstrin_homology.
DR   InterPro; IPR018159; Spectrin/alpha-actinin.
DR   InterPro; IPR016343; Spectrin_bsu.
DR   InterPro; IPR001605; Spectrin_PH.
DR   InterPro; IPR002017; Spectrin_repeat.
DR   Gene3D; G3DSA:1.10.418.10; Calponin-homology; 2.
DR   Gene3D; G3DSA:2.30.29.30; PH_type; 1.
DR   Pfam; PF00307; CH; 2.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00435; Spectrin; 17.
DR   PIRSF; PIRSF002297; Spectrin_beta_subunit; 1.
DR   PRINTS; PR00683; SPECTRINPH.
DR   SMART; SM00033; CH; 2.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00150; SPEC; 17.
DR   SUPFAM; SSF47576; Calponin-homology; 1.
DR   PROSITE; PS00019; ACTININ_1; 1.
DR   PROSITE; PS00020; ACTININ_2; 1.
DR   PROSITE; PS50021; CH; 2.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   HOGENOMDNA; CAEELV.PE1966; -.
KW   K11C4.361039200367fold_1320000031; K11C4.3b1.12200.62fold_1320000031;
KW   Q9U9J8_CAEEL; AF166169; U64854;
KW   Actin-binding; Complete proteome; Reference proteome; Repeat.
SQ   SEQUENCE   2302 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MATVDGNSGA YTQDEDYDDN SSARLFERSR IKALADEREL VQKKTFTKWV NSHLVRVSCK
     VQDLYMDMRD GKMLLRLLAV LSGERLPKPT PGKMRIHCLE NVEKGLQFLR NQHVHLENLG
     SHDIVDGNSR LTLGLIWTII LRFQIQDITF EDADNHETRS AKEALLLWCQ MKTAGYPNVN
     VKNFSTSWRD GLAFNALIHK HRPDLVDYDN LQKSNALYNL QSAFDTAENQ LGLAKFLDAE
     DVNVDQPDEK SIITYVVTYY HYFNKLKQDN IQGKRIGKVI NELMENDKMI NRYETLSSDL
     LEWINAKIQL LNERHFENNL EGVQRQLTEF NDYRTQEKPP KFDEKGELEV LLFTLQSAMR
     ANNQRPFVPR EGKLIADINR AWQSLEKAEH ERELVLKEEL IRQEKLEQLA ARFNRKAEMR
     ETWLTENQRL VSQDNFGNDL SSVEAATKKH EAIETDIFAY EERVQAVVAV AGELEAENYH
     DQAKINERKE NVLQLWNYLF QLLLARRVRL ELSMAIQKIF HDMLLTLDLM DDIKSRLLSE
     DLGAHLMDVE DLLQKHALLE SDINIIGERV NNSIAQAQRF RNPDGPDGSG YKPVEPGTID
     ERSDVLQKRY KELLDLAAER KRRLEDNKRL CQFWWDVAEL EHGIKEQEQV LSSTDTGRDI
     VTVSHLLAKH KNAENNLRDL EKYLDRLDVS GKELQDESIP GSDNIPPRLA EIRDYINKLK
     ELSASRKERL AGGVEYYQFF TDADDVDRYL YDTLRVMSSE DVGKDEGTVQ LLLKKHDDVH
     DELQNFDQHI KVLHAKAESL PQEAREHPDI RQRLDTTLKQ KAELENLSQL RKQRLIDALS
     LYKLYSDADS VESWIDEKGK LLATLVPGRD IEEVEIMKHR FDTLEQDMKN QEAKVTNVND
     LARQLLNVEH PNSDDILHRQ NKLNARWAQL RDMVDQKRNE LERAHRLETF RIDCQETVTW
     IEDKTRVLED SDALTNDLSG VMKLQRRLSM MERDLGAIQA KLDSLHKEAD DIERERPQEA
     QAIREDIKRI HQVWDILNKK VREHEAKLDE AGDLQRFLRD LDHFQAWLTA TQRQVASEEE
     PQSLAEAEQL LNQHAAIREE IDGYAEDYKK MRAMGDRVTQ DQTDPQYMFL RQRLAGLQEG
     WEELQRMWDN RQHLLSQGLN LQMFLRDAKQ AEVMLSQQEN YLAKDDIPQS LEQAENQLKR
     HQDFITTMDA NDEKIRAVGM FGDQLCQDGH YAADKIHKKA RNIDERRGAN REKAQEVLKK
     LKDALSLQQF LSDCDELREW IEEKMIRAQD ETYRDAKTIT SKFVRHQAFQ SELAANKERL
     DQLKHAAINL GDDKPEYHGT IDPQIEELAT QWDELEKTTE EKGQKLFDAN RQQLYVQSIA
     DMKEWATQLE NEMTREDQPG DLTTVNVAMQ KQHLIETEMI KKAQHIDQLM EMEPQLEELH
     PDELENIKAH RLAVQEQLQR LQAPLDDRRK ALERKKAAFQ FGRDVDDEKL WISERLVLAK
     AQNLGESLPD CHRLQKNLQL LSNEIDNHEP WINQICNNGQ ELIDEGHANG PAFEKKIQEL
     RSAWQELKEA VKDRKGDLGE SEKAHQFLYD CGEAEAWMSE QELYMMQDER GKDEFSTKNQ
     IKKHERLQSD IDKFADTIRA LATKAHKFVE EKSPLTEQIQ VRQAQIEKLY AGLQDLSKER
     RKRLEETLEL YALHREIDDL LQWIADKEVV AGSQENGQDY EHVQMLQERF QQFARDTENI
     GSERVANAND GCDTLIGHGH TDAPTIALWK DSLNEAWENL LELMDTRAQI LEASRLLHKF
     YHDCRDCLSR IMEKTHAMPD DLGRDSSSVG ALSRKHQNYL KDIAAIGEQV AQIERDAAEL
     RDGYAGDKAL DIGSRESEVV KAWRHLRGLC DARTSRLMDT SDLFKFMNMV RDLLLWMDEV
     KREMNSQERP KDVSGVELLM NNHQSLKAEI DAREENFNAC ISLGRDLLNR KHYASSEIEK
     KLIKLTTERA EMMRRWEDRW EYLQLILEVY QFARDAAVAE SWLFAQEPYL ISKEYGRNLE
     ETIKLIKKHE AFEKSAFAQE ERFLALEKLT TFELKETQHR EEETAKRRGP AHIGSPSRST
     PAAETSFGAQ DDDADITHSS LEGHRKSSHE KRLAHSESSS WRKSLARAAK FDSKDPKGAK
     QGEAFEGTLI RKHTYESLDR KAANRSWEKL YAVLRQNELS FYKDPKHRDE SVHGEPPMAL
     PGCSVNVASD YQKKKNVLSL RLPIGAEYLF QCGSEEDMQR WLTELQVATG QAQLEEASRS
     QTLPAEGSAT KKKGGFFSRG KK
//

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