(data stored in ACNUC3582 zone)

HOGENOM: CAEELX_PE652

ID   CAEELX_PE652                         STANDARD;      PRT;   709 AA.
AC   CAEELX_PE652; Q21376;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Putative extracellular sulfatase Sulf-1 homolog;
DE   Short=CeSulf-1; EC=3.1.6 -;Flags: Precursor; (CAEELX.PE652).
GN   Name=sul-1; ORFNames=K09C4.8;
OS   CAENORHABDITIS ELEGANS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Pseudocoelomata; Nematoda;
OC   Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CAEELX.PE652.
CC       Caenorhabditis elegans chromosome X WS210  sequence 1..17718854
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:SULF1_CAEEL
CC   -!- COFACTOR: Binds 1 calcium ion per subunit (By similarity).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum (By similarity). Golgi
CC       apparatus, Golgi stack (By similarity). Cell surface (By
CC       similarity). Note=Also localized on the cell surface (By
CC       similarity).
CC   -!- PTM: The conversion to 3-oxoalanine (also known as C-
CC       formylglycine, FGly), of a serine or cysteine residue in
CC       prokaryotes and of a cysteine residue in eukaryotes, is critical
CC       for catalytic activity (By similarity).
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC   -!- GENE_FAMILY: HOG000290161 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Caenorhabditis_elegans;K09C4.8;K09C4.8;K09C4.8.
DR   EMBL; U43375; - ;
DR   UniProtKB/Swiss-Prot; Q21376; -.
DR   EMBL; U43375; AAA83618.1; -; Genomic_DNA.
DR   PIR; T16584; T16584.
DR   RefSeq; NP_508560.1; NM_076159.2.
DR   UniGene; Cel.700; -.
DR   ProteinModelPortal; Q21376; -.
DR   SMR; Q21376; 271-378.
DR   STRING; Q21376; -.
DR   EnsemblMetazoa; K09C4.8; K09C4.8; K09C4.8.
DR   GeneID; 180619; -.
DR   KEGG; cel:K09C4.8; -.
DR   NMPDR; fig|6239.3.peg.22827; -.
DR   UCSC; K09C4.8; c. elegans.
DR   CTD; 180619; -.
DR   WormBase; K09C4.8; CE04736; WBGene00006308; sul-1.
DR   eggNOG; meNOG04983; -.
DR   GeneTree; EMGT00050000008273; -.
DR   InParanoid; Q21376; -.
DR   OMA; HEKKSIG; -.
DR   PhylomeDB; Q21376; -.
DR   NextBio; 910136; -.
DR   ArrayExpress; Q21376; -.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
DR   GO; GO:0017095; F:heparan sulfate 6-O-sulfotransferase activity; IMP:WormBase.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR   GO; GO:0015015; P:heparan sulfate proteoglycan biosynthetic process, enzymatic modification; IMP:WormBase.
DR   InterPro; IPR017849; Alkaline_Pase-like_a/b/a.
DR   InterPro; IPR017850; Alkaline_phosphatase_core.
DR   InterPro; IPR000917; Sulfatase.
DR   Gene3D; G3DSA:3.40.720.10; Alk_phosphtse; 4.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline_phosphatase_core; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
DR   PROSITE; PS00149; SULFATASE_2; FALSE_NEG.
DR   HOGENOMDNA; CAEELX.PE652; -.
KW   K09C4.800149200367fold_1320000031; K09C4.8.21.1.20.62fold_1320000031;
KW   U43375;
KW   Calcium; Complete proteome; Endoplasmic reticulum; Glycoprotein;
KW   Golgi apparatus; Hydrolase; Metal-binding; Reference proteome; Signal.
SQ   SEQUENCE   709 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MISNLRISNY FIIFYVLFLI IPIKVTSIHF VDSQHNVILI LTDDQDIELG SMDFMPKTSQ
     IMKERGTEFT SGYVTTPICC PSRSTILTGL YVHNHHVHTN NQNCTGVEWR KVHEKKSIGV
     YLQEAGYRTA YLGKYLNEYD GSYIPPGWDE WHAIVKNSKF YNYTMNSNGE REKFGSEYEK
     DYFTDLVTNR SLKFIDKHIK IRAWQPFALI ISYPAPHGPE DPAPQFAHMF ENEISHRTGS
     WNFAPNPDKQ WLLQRTGKMN DVHISFTDLL HRRRLQTLQS VDEGIERLFN LLRELNQLWN
     TYAIYTSDHG YHLGQFGLLK GKNMPYEFDI RVPFFMRGPG IPRNVTFNEI VTNVDIAPTM
     LHIAGVPKPA RMNGRSLLEL VALKKKKKKH MTALKPWRDT ILIERGKMPK LKKIRDRYIK
     QKKKFNKENR LSKECKRRKW QRDCVHGQLW KCYYTVEDRW RIYKCRDNWS DQCSCRKKRE
     ISNYDDDDID EFLTYADREN FSEGHEWYQG EFEDSGEVGE ELDGHRSKRG ILSKCSCSRN
     VSHPIKLLEQ KMSKKHYLKY KKKPQNGSLK PKDCSLPQMN CFTHTASHWK TPPLWPEELG
     EFCFCQNCNN NTYWCLRTKN ETHNFLYCEF VTEFISFYDF NTDPDQLINA VYSLDIGVLE
     QLSEQLRNLR KCKNRQCEIW STSQMLRSPK LVDLRVNEKS FLTYQPEKT
//

If you have problems or comments...

PBIL Back to PBIL home page