(data stored in ACNUC7421 zone)

HOGENOM: CAUCN_1_PE1006

ID   CAUCN_1_PE1006                       STANDARD;      PRT;   554 AA.
AC   CAUCN_1_PE1006; B8H2R9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Urocanate hydratase; Short=Urocanase; EC=4.2.1 49;AltName:
DE   Full=Imidazolonepropionate hydrolase; (CAUCN_1.PE1006).
GN   Name=hutU; OrderedLocusNames=CCNA_01008;
OS   CAULOBACTER CRESCENTUS NA1000.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=565050;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CAUCN_1.PE1006.
CC       Caulobacter crescentus NA1000 chromosome, complete genome.
CC       (1809 nt) ;
CC   -!- ANNOTATIONS ORIGIN:HUTU_CAUCN
CC   -!- CATALYTIC ACTIVITY: 3-(5-oxo-4,5-dihydro-3H-imidazol-4-
CC       yl)propanoate = urocanate + H(2)O.
CC   -!- COFACTOR: Binds 1 NAD per subunit (By similarity).
CC   -!- PATHWAY: Amino-acid degradation; L-histidine degradation into L-
CC       glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the urocanase family.
CC   -!- GENE_FAMILY: HOG000237606 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B8H2R9; -.
DR   EMBL; CP001340; ACL94473.1; -; Genomic_DNA.
DR   RefSeq; YP_002516381.1; NC_011916.1.
DR   ProteinModelPortal; B8H2R9; -.
DR   SMR; B8H2R9; 10-551.
DR   STRING; B8H2R9; -.
DR   GeneID; 7333140; -.
DR   GenomeReviews; CP001340_GR; CCNA_01008.
DR   KEGG; ccs:CCNA_01008; -.
DR   OMA; IRQMAFE; -.
DR   ProtClustDB; PRK05414; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016153; F:urocanate hydratase activity; IEA:EC.
DR   GO; GO:0006548; P:histidine catabolic process; IEA:InterPro.
DR   HAMAP; MF_00577; HutU; 1; -.
DR   InterPro; IPR000193; Urocanase.
DR   InterPro; IPR023636; Urocanase_CS.
DR   InterPro; IPR023637; Urocanase_dom.
DR   Pfam; PF01175; Urocanase; 1.
DR   PIRSF; PIRSF001423; Urocanate_hydrat; 1.
DR   SUPFAM; SSF111326; Urocanase; 1.
DR   TIGRFAMs; TIGR01228; HutU; 1.
DR   PROSITE; PS01233; UROCANASE; 1.
DR   HOGENOMDNA; CAUCN_1.PE1006; -.
KW   urocanate hydratase;
KW   Complete proteome; Cytoplasm; Histidine metabolism; Lyase; NAD.
SQ   SEQUENCE   554 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTRRDTTRVI RPATGPERTC KSWLTEAALR MLMNNLHPDV AERPEELVVY GGIGRAARDW
     ESYDKIVETL RRLEDDETLL VQSGKPVGVF RTHADAPRVL IANSNLVPRW ASWEHFNELD
     RKGLAMYGQM TAGSWIYIGA QGIVQGTYET FVEMGRQHYG GDLSGRWLLT AGLGGMGGAQ
     PLAAVMAGAA CLAIECQPSS IEMRLRTGYL DRSTDKVEEA LAWIEESCAA KTPISVGLLG
     NAAELLPELF KRGVRPDLLT DQTSAHDPVN GYLPAGWSLE RWHAMRDQDP PQVAEAAKAS
     MAAHVKAMLD FQAAGVPTVD YGNNIRQMAL EEGVTNAFDF PGFVPAYIRP LFCRGVGPFR
     WAALSGDPED IAKTDAKVKE LIPDNPHLHN WLDMAGQKIR FQGLPARICW VGLGDRHRLG
     LAFNEMVAKG ELKAPIVIGR DHLDSGSVAS PNRETEAMRD GSDAVSDWPL LNALLNTASG
     ATWVSLHHGG GVGMGFSQHA GMVIVCDGTE AAAKRVARVL WNDPATGVMR HADAGYDIAL
     ACAREKGLDL PGIL
//

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