(data stored in SCRATCH zone)

HOGENOM: CHABO1_1_PE116

ID   CHABO1_1_PE116                       STANDARD;      PRT;   168 AA.
AC   CHABO1_1_PE116; Q5L6Z4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Crossover junction endodeoxyribonuclease ruvC; EC=3.1.22
DE   4;AltName: Full=Holliday junction nuclease ruvC;AltName: Full=Holliday
DE   junction resolvase ruvC; (CHABO1_1.PE116).
GN   Name=ruvC; OrderedLocusNames=CAB118;
OS   CHLAMYDOPHILA ABORTUS S26/3.
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydophila.
OX   NCBI_TaxID=218497;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CHABO1_1.PE116.
CC       Chlamydophila abortus S26/3, complete genome.
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:RUVC_CHLAB
CC   -!- FUNCTION: Nuclease that resolves Holliday junction intermediates
CC       in genetic recombination. Cleaves the cruciform structure in
CC       supercoiled DNA by nicking to strands with the same polarity at
CC       sites symmetrically opposed at the junction in the homologous arms
CC       and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl
CC       group (By similarity).
CC   -!- CATALYTIC ACTIVITY: Endonucleolytic cleavage at a junction such as
CC       a reciprocal single-stranded crossover between two homologous DNA
CC       duplexes (Holliday junction).
CC   -!- COFACTOR: Binds 1 magnesium ion per subunit (By similarity).
CC   -!- SIMILARITY: Belongs to the ruvC family.
CC   -!- GENE_FAMILY: HOG000012181 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5L6Z4; -.
DR   EMBL; CR848038; CAH63576.1; -; Genomic_DNA.
DR   RefSeq; YP_219548.2; NC_004552.2.
DR   ProteinModelPortal; Q5L6Z4; -.
DR   GeneID; 3338197; -.
DR   GenomeReviews; CR848038_GR; CAB118.
DR   KEGG; cab:CAB118; -.
DR   OMA; GRADKKQ; -.
DR   PhylomeDB; Q5L6Z4; -.
DR   ProtClustDB; PRK00039; -.
DR   BioCyc; CABO218497:CAB118-MON; -.
DR   GO; GO:0008821; F:crossover junction endodeoxyribonuclease activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   HAMAP; MF_00034; RuvC; 1; -.
DR   InterPro; IPR012337; RNaseH-like.
DR   InterPro; IPR020563; X-over_junc_endoDNase_Mg_BS.
DR   InterPro; IPR002176; X-over_junc_endoDNase_RuvC.
DR   Pfam; PF02075; RuvC; 1.
DR   PRINTS; PR00696; RSOLVASERUVC.
DR   SUPFAM; SSF53098; RNaseH_fold; 1.
DR   TIGRFAMs; TIGR00228; RuvC; 1.
DR   PROSITE; PS01321; RUVC; 1.
DR   HOGENOMDNA; CHABO1_1.PE116; -.
KW   Complete proteome; DNA damage; DNA recombination; DNA repair;
KW   Hydrolase; Magnesium; Metal-binding; Nuclease.
SQ   SEQUENCE   168 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTQLIMGIDP GTLVSGYAII LVEQRYKIRA HSYGAIRLSS KDSLTQRYKQ LFQTLSGVLD
     NVTPDAVVLE TQYVHKNPQS AIKLGMGRGV LVLAAALRDI PVFEYTPNVA KRAVVGKGNA
     SKQQVQLMVS KILNIPDVLN SDCEDIADAF ALAICHAHTS AYTCLGVR
//

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