(data stored in ACNUC18020 zone)

HOGENOM: CHICK10_PE100

ID   CHICK10_PE100                        STANDARD;      PRT;   530 AA.
AC   CHICK10_PE100; P79760;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Cytochrome P450 1A4; EC=1.14.14 1;AltName:
DE   Full=CYPIA4;AltName: Full=Cytochrome P450 TCDDAHH; (CHICK10.PE100).
GN   Name=CYP1A4;
OS   GALLUS GALLUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Sauropsida; Sauria; Archosauria;
OC   Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae;
OC   Galliformes; Phasianidae; Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CHICK10.PE100.
CC       Gallus gallus chromosome 10 WASHUC2  sequence 1..22556432 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:CP1A4_CHICK
CC   -!- FUNCTION: Cytochromes P450 are a group of heme-thiolate
CC       monooxygenases. In liver microsomes, this enzyme is involved in an
CC       NADPH-dependent electron transport pathway. It oxidizes a variety
CC       of structurally unrelated compounds, including steroids, fatty
CC       acids, and xenobiotics.
CC   -!- CATALYTIC ACTIVITY: RH + reduced flavoprotein + O(2) = ROH +
CC       oxidized flavoprotein + H(2)O.
CC   -!- COFACTOR: Heme group (By similarity).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral
CC       membrane protein. Microsome membrane; Peripheral membrane protein.
CC   -!- INDUCTION: By 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC   -!- GENE_FAMILY: HOG000036991 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Gallus_gallus;ENSGALG00000001325;ENSGALT00000040012;ENSGALP00000039219.
DR   EMBL; X99453; - ;
DR   UniProtKB/Swiss-Prot; P79760; -.
DR   EMBL; X99453; CAA67815.1; -; mRNA.
DR   IPI; IPI00603769; -.
DR   RefSeq; NP_990478.1; NM_205147.1.
DR   UniGene; Gga.43121; -.
DR   ProteinModelPortal; P79760; -.
DR   SMR; P79760; 44-523.
DR   STRING; P79760; -.
DR   GeneID; 396052; -.
DR   KEGG; gga:396052; -.
DR   CTD; 396052; -.
DR   eggNOG; veNOG06314; -.
DR   InParanoid; P79760; -.
DR   OrthoDB; EOG4WSW9D; -.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
DR   GO; GO:0070330; F:aromatase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR008066; Cyt_P450_E_grp-I_CYP1.
DR   Gene3D; G3DSA:1.10.630.10; Cyt_P450; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR01683; EP450ICYP1A.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome_P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
DR   HOGENOMDNA; CHICK10.PE100; -.
KW   ENSGALG00000001325fold_1320000031; ENSGALP00000039219fold_1320000031;
KW   Q9PRY5_CHICK; X99453;
KW   Complete proteome; Endoplasmic reticulum; Heme; Iron; Membrane;
KW   Metal-binding; Microsome; Monooxygenase; Oxidoreductase;
KW   Reference proteome.
SQ   SEQUENCE   530 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAAGPQAAME QASSPGLISA TEVLVAAATF CLLLLLTQTR RQHAPKGLRS PPGPRGLPML
     GSVLELRKDP HLVLTRLSRK YGDVMEVTIG SRPVVVLSGL ETIKQALVRQ AEDFMGRPDL
     PSWQYVSNGH SLAFSYECGD AWKARRKLAQ NALKTFSIAA SPTASSSCLL EEHVSTEASY
     LVTKFLQLME EKQSFNPNSY LMVSVANVIC AICFGKRYDH DDQELLSVVN MNTEFGDVAA
     AGNPADFIPL LRYLPNRAMA AFKDVNARFS AFVQKIVQNH YSTFDKEHIR DVTDSLIGHC
     QEKKTGEDVR VQPSDESIIS IVNDLFGAGF DTVTTALSWC MMYAALYPHI QKKIQAELDQ
     TIGRERRPRL SDRGMLPYTE AFILEAFRHS SLLPFTIPHC TTKDTVLNGY YIPKDTCVFI
     NQWQANHDEK IWKDPSSFKP ERFLNAAGTE LSRTEADKVL IFGLGKRRCI GESIGRWEVF
     LFLTTILQQL EISLAPGQRV DITPQYGLTM KYKQCECFQM KKRFPSKGSA
//

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