(data stored in ACNUC17492 zone)

HOGENOM: CHICK8_PE58

ID   CHICK8_PE58                          STANDARD;      PRT;   209 AA.
AC   CHICK8_PE58; Q7SZC6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Regulator of G-protein signaling 4; Short=RGS4;
DE   (CHICK8.PE58).
GN   Name=RGS4;
OS   GALLUS GALLUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Sauropsida; Sauria; Archosauria;
OC   Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae;
OC   Galliformes; Phasianidae; Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CHICK8.PE58.
CC       Gallus gallus chromosome 8 WASHUC2  sequence 1..30671729 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:RGS4_CHICK
CC   -!- FUNCTION: Inhibits signal transduction by increasing the GTPase
CC       activity of G protein alpha subunits thereby driving them into
CC       their inactive GDP-bound form. Activity on G(z)-alpha is inhibited
CC       by phosphorylation of the G-protein. Activity on G(z)-alpha and
CC       G(i)-alpha-1 is inhibited by palmitoylation of the G-protein (By
CC       similarity).
CC   -!- TISSUE SPECIFICITY: Expressed in the developing nervous system.
CC   -!- PTM: Palmitoylated on Cys-2 and/or Cys-12 (By similarity).
CC   -!- PTM: Phosphorylated by cyclic GMP-dependent protein kinase (By
CC       similarity).
CC   -!- SIMILARITY: Contains 1 RGS domain.
CC   -!- GENE_FAMILY: HOG000233512 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Gallus_gallus;ENSGALG00000002564;ENSGALT00000004050;ENSGALP00000004041.
DR   EMBL; AF090081; - ;
DR   EMBL; AF090091; - ;
DR   EMBL; AY297457; - ;
DR   UniProtKB/Swiss-Prot; Q7SZC6; -.
DR   EMBL; AY297457; AAP57222.1; -; mRNA.
DR   IPI; IPI00585502; -.
DR   RefSeq; NP_989716.1; NM_204385.1.
DR   UniGene; Gga.5334; -.
DR   HSSP; P49799; 1AGR.
DR   ProteinModelPortal; Q7SZC6; -.
DR   SMR; Q7SZC6; 51-178.
DR   STRING; Q7SZC6; -.
DR   PRIDE; Q7SZC6; -.
DR   GeneID; 378901; -.
DR   KEGG; gga:378901; -.
DR   CTD; 5999; -.
DR   eggNOG; veNOG15014; -.
DR   InParanoid; Q7SZC6; -.
DR   OrthoDB; EOG4PK297; -.
DR   GO; GO:0005737; C:cytoplasm; IBA:RefGenome.
DR   GO; GO:0005886; C:plasma membrane; IBA:RefGenome.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000342; Regulat_G_prot_signal.
DR   InterPro; IPR024066; Regulat_G_prot_signal_dom1.
DR   InterPro; IPR016137; Regulat_G_prot_signal_superfam.
DR   Gene3D; G3DSA:1.10.196.10; G3DSA:1.10.196.10; 1.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulat_G_prot_signal_superfam; 1.
DR   PROSITE; PS50132; RGS; 1.
DR   HOGENOMDNA; CHICK8.PE58; -.
KW   ENSGALG00000002564fold_1320000031; ENSGALP00000004041fold_1320000031;
KW   Q9PVI4_CHICK; Q9W7I7_CHICK; AF090081; AF090091; AY297457;
KW   Complete proteome; Lipoprotein; Palmitate; Phosphoprotein;
KW   Reference proteome; Signal transduction inhibitor.
SQ   SEQUENCE   209 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCKGLAALPA TCLKSAKDMK HRLGVLLQKS ESCDYGSSQG KKEKVSPSQR VSQEEVKKWA
     ESLENLIHHD RGLAAFRAFL KSEYSEENIE FWVSCEDYKK TKSPAKLSTK ARKIYDEFIS
     VQATKEVNLD SCTREKTSHN MLEPTLSCFD EAQRKIFTLM EKDSYRRFLK SPYYLDLVSP
     PRAGCGPENC KRAHAHALDC NSNIISQCA
//

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